The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …

Obesity and substantially increased risk of metabolic diseases have become a global
epidemic. microRNAs have attracted a great deal of attention as a potential therapeutic …

Adipose tissue undergoes thermogenic remodeling in response to thermal stress and
metabolic cues, playing a crucial role in regulating energy expenditure and metabolic …

Although the adipose tissue (AT) is a central metabolic organ in the regulation of whole-
body energy homeostasis, it is also an important endocrine and immunological organ. As an …

Insulin stimulates glucose uptake into adipocytes via mTORC2/AKT signaling and GLUT4
translocation and directs glucose carbons into glycolysis, glycerol for TAG synthesis, and de …

Mammals maintain a constant core body temperature through adaptive thermogenesis
which includes shivering and non-shivering thermogenesis. Non-shivering thermogenesis …

Mammals maintain thermoregulation in the face of cold environmental temperatures by
activating bioenergetic mechanisms that increase heat production. Included in this response …

Adipose tissue is composed of adipocytes, stromal vascular fraction, nerves, surrounding
immune cells, and the extracellular matrix. Under various physiological or pathological …

Research focusing on adipose immunometabolism has been expanded from inflammation
in white fat during obesity development to immune cell function regulating thermogenic fat …

T Helper 17 (Th17) cells are adaptive immune cells that play myriad roles in the body.
Immune–endocrine interactions are vital in endocrine organs during pathological states …