History, discovery, and classification of lncRNAs
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
Towards a complete map of the human long non-coding RNA transcriptome
Gene maps, or annotations, enable us to navigate the functional landscape of our genome.
They are a resource upon which virtually all studies depend, from single-gene to genome …
They are a resource upon which virtually all studies depend, from single-gene to genome …
Genome-wide analysis of human long noncoding RNAs: a provocative review
Do long noncoding RNAs (lncRNAs) contribute little or substantively to human biology? To
address how lncRNA loci and their transcripts, structures, interactions, and functions …
address how lncRNA loci and their transcripts, structures, interactions, and functions …
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease
Long non-coding RNA (lncRNA) genes have well-established and important impacts on
molecular and cellular functions. However, among the thousands of lncRNA genes, it is still …
molecular and cellular functions. However, among the thousands of lncRNA genes, it is still …
HRT Atlas v1. 0 database: redefining human and mouse housekee** genes and candidate reference transcripts by mining massive RNA-seq datasets
BW Hounkpe, F Chenou, F de Lima… - Nucleic acids …, 2021 - academic.oup.com
Housekee** (HK) genes are constitutively expressed genes that are required for the
maintenance of basic cellular functions. Despite their importance in the calibration of gene …
maintenance of basic cellular functions. Despite their importance in the calibration of gene …
The FLC Locus: A Platform for Discoveries in Epigenetics and Adaptation
Our understanding of the detailed molecular mechanisms underpinning adaptation is still
poor. One example for which mechanistic understanding of regulation has converged with …
poor. One example for which mechanistic understanding of regulation has converged with …
Targeting and engineering long non-coding RNAs for cancer therapy
RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …
Circular RNA expression in human hematopoietic cells is widespread and cell-type specific
BP Nicolet, S Engels, F Aglialoro… - Nucleic acids …, 2018 - academic.oup.com
Hematopoietic stem cells differentiate into a broad range of specialized blood cells. This
process is tightly regulated and depends on transcription factors, micro-RNAs, and long non …
process is tightly regulated and depends on transcription factors, micro-RNAs, and long non …
Evaluation of efficacy of non-coding RNA in abiotic stress management of field crops: Current status and future prospective
Abiotic stresses are responsible for the major losses in crop yield all over the world. Stresses
generate harmful ROS which can impair cellular processes in plants. Therefore, plants have …
generate harmful ROS which can impair cellular processes in plants. Therefore, plants have …
Exosomal long non-coding RNAs in lung diseases
Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their
secretion within exosomes are a window that could further explain the regulation, the …
secretion within exosomes are a window that could further explain the regulation, the …