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Seronegative autoimmune diseases: A challenging diagnosis
Autoimmune diseases (AID) are increasingly prevalent conditions which comprise more
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …
Origins and immunopathogenesis of autoimmune central nervous system disorders
The field of autoimmune neurology is rapidly evolving, and recent discoveries have
advanced our understanding of disease aetiologies. In this article, we review the key …
advanced our understanding of disease aetiologies. In this article, we review the key …
Neurological adverse events of immune checkpoint inhibitors and the development of paraneoplastic neurological syndromes
A Farina, M Villagrán-García, A Vogrig… - The Lancet …, 2024 - thelancet.com
Immune checkpoint inhibitors, a class of oncological treatments that enhance antitumour
immunity, can trigger neurological adverse events closely resembling paraneoplastic …
immunity, can trigger neurological adverse events closely resembling paraneoplastic …
Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease
T Grüter, FE Möllers, A Tietz, J Dargvainiene, N Melzer… - Brain, 2023 - academic.oup.com
Anti-IgLON5 disease is a newly defined clinical entity characterized by a progressive course
with high disability and mortality rate. While precise pathogenetic mechanisms remain …
with high disability and mortality rate. While precise pathogenetic mechanisms remain …
Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity
While the spectrum of neurological immune checkpoint inhibitor-related adverse events is
expanding, patients' outcomes are not well documented. This study aimed to assess …
expanding, patients' outcomes are not well documented. This study aimed to assess …
Paraneoplastic neurological syndromes: a practical approach to diagnosis and management
Paraneoplastic neurological syndromes (PNS) are the immune-mediated effects of a remote
cancer and are characterised by an autoantibody response against antigens expressed by …
cancer and are characterised by an autoantibody response against antigens expressed by …
Mimics of autoimmune encephalitis: validation of the 2016 clinical autoimmune encephalitis criteria
RW Van Steenhoven, JM de Vries… - Neurology …, 2023 - neurology.org
Background and Objectives The clinical criteria for autoimmune encephalitis (AE) were
proposed by Graus et al. in 2016. In this study, the AE criteria were validated in the real …
proposed by Graus et al. in 2016. In this study, the AE criteria were validated in the real …
Paraneoplastic neurologic disorders
M Gilligan, C McGuigan, A McKeon - Current neurology and neuroscience …, 2023 - Springer
Abstract Purpose of Review To provide an overview and highlight recent updates in the field
of paraneoplastic neurologic disorders. Recent Findings The prevalence of paraneoplastic …
of paraneoplastic neurologic disorders. Recent Findings The prevalence of paraneoplastic …
Anti-Hu antibodies in patients with neurologic side effects of immune checkpoint inhibitors
A Farina, M Villagrán-García… - Neurology …, 2022 - neurology.org
Background and Objectives To clinically characterize post–immune checkpoint inhibitor (ICI)
Hu antibody (Ab) neurologic disorders, we analyzed Hu-Ab–positive patients with …
Hu antibody (Ab) neurologic disorders, we analyzed Hu-Ab–positive patients with …
Paraneoplastic neurological syndromes of the central nervous system: pathophysiology, diagnosis, and treatment
L Marsili, S Marcucci, J LaPorta, M Chirra, AJ Espay… - Biomedicines, 2023 - mdpi.com
Paraneoplastic neurological syndromes (PNS) include any symptomatic and non-metastatic
neurological manifestations associated with a neoplasm. PNS associated with antibodies …
neurological manifestations associated with a neoplasm. PNS associated with antibodies …