Automatic CT segmentation of proximal femur has a great potential for use in orthopedic
diseases, especially in the imaging-based assessments of hip fracture risk. In this study, we …

In this cross‐sectional study, we aimed to predict age‐related changes in bone
microarchitecture and strength at the distal radius (DR) and distal tibia (DT) in 644 Canadian …

Magnetic resonance imaging (MRI) plays a pivotal role for assessment of the
musculoskeletal system. It is currently the clinical modality of choice for evaluation of soft …

Results of recent imaging studies and theoretical models suggest that the superior femoral
neck is a location of local weakness due to an age-related thinning of the cortex, and thus …

Age-related changes in lumbar vertebral microarchitecture are evaluated, as assessed by
trabecular bone score (TBS), in a cohort of 5,942 French women. The magnitude of TBS …

We investigated age-and gender-related variation of both cortical and trabecular
microstructure in human femoral neck. We found that age-related change of cortical porosity …

It is not clear which non-invasive method is most effective for predicting strength of the
proximal femur in those at highest risk of fracture. The primary aim of this study was to …

The anatomic distribution of cortical and cancellous bone in the femoral neck may be critical
in determining resistance to fracture. We investigated the effects of aging on femoral neck …

The biomechanical mechanisms underlying sex‐specific differences in age‐related
vertebral fracture rates are ill defined. To gain insight into this issue, we used finite element …

Bone mineral density (BMD) as assessed by dual energy X-ray absorptiometry (DXA)
constitutes the gold standard for osteoporosis diagnosis. However, DXA does not take into …