Sedative Effects of Daidzin, Possibly Through the GABAA Receptor Interaction Pathway: In Vivo Approach with Molecular Dynamic Simulations

MT Islam, MS Bhuia, S Sheikh, R Hasan… - Journal of Molecular …, 2024 - Springer
The soy isoflavone daidzin (DZN) has been considered a hopeful bioactive compound
having diverse biological activities, including anxiolytic, memory-enhancing, and …

In-silico study unveils potential phytocompounds in Andrographis paniculata against E6 protein of the high-risk HPV-16 subtype for cervical cancer therapy

MA Islam, MS Hossain, S Hasnat, MH Shuvo, S Akter… - Scientific Reports, 2024 - nature.com
Despite therapeutic advancements, cervical cancer caused by high-risk subtypes of the
human papillomavirus (HPV) remains a leading cause of cancer-related deaths among …

Anti-inflammatory effects of thymol: an emphasis on the molecular interactions through in vivo approach and molecular dynamic simulations

MT Islam, MH Bappi, MS Bhuia, SA Ansari… - Frontiers in …, 2024 - frontiersin.org
Thymol (THY), as the natural monoterpene phenol, acts against oxidative stress and
inflammatory processes. This study aimed to evaluate the anti-inflammatory effects and …

Assessing anti oxidant, antidiabetic potential and GCMS profiling of ethanolic root bark extract of Zanthoxylum rhetsa (Roxb.) DC: Supported by in vitro, in vivo and in …

AK Barman, S Mahadi, MA Hossain, R Begum… - PLoS …, 2024 - journals.plos.org
Zanthoxylum rhetsa (ZR) is used traditionally to manage a variety of ailments, including
diabetes. Oxidative stress may accelerate the diabetic condition. The available antidiabetic …

Waste to Medicine: Evidence from Computational Studies on the Modulatory Role of Corn Silk on the Therapeutic Targets Implicated in Type 2 Diabetes Mellitus

A Akoonjee, AA Lanrewaju, FO Balogun, NP Makunga… - Biology, 2023 - mdpi.com
Simple Summary Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance
and/or defective insulin production in the human body. Corn silk (CS), an abundant, readily …

Abietic acid antagonizes the anti-inflammatory effects of celecoxib and ketoprofen: Preclinical assessment and molecular dynamic simulations

R Hasan, MS Bhuia, R Chowdhury, S Saha… - Computers in Biology …, 2024 - Elsevier
The present work is designed to explore the anti-inflammatory properties of AA and its
modulatory effects on celecoxib (CEL) and ketoprofen (KET) through in vitro, ex vivo, in vivo …

[PDF][PDF] Evaluation of the Antidiabetic Effects of Methanolic Extracts of Neem (Azadirachta indica) Seeds on the Streptozotocin-induced Wistar Rats.

AM Abduallah, AE Ahmed, MA Bajaber… - Pakistan Veterinary …, 2023 - pvj.com.pk
Plants are among the most prominent candidates in herbal medicine. Vast research is being
performed for effective plants against diabetes. This experiment aimed to evaluate the …

Profiling of antioxidant properties and identification of potential analgesic inhibitory activities of Allophylus villosus and Mycetia sinensis employing in vivo, in vitro, and …

MNK Azam, P Biswas, A Khandker, MMI Tareq… - Journal of …, 2025 - Elsevier
Ethnopharmacological relevance The traditional use of plants for medicinal purposes, called
phytomedicine, has been known to provide relief from pain. In Bangladesh, the Chakma …

[HTML][HTML] Exploring the therapeutic targets of stevioside in management of type 2 diabetes by network pharmacology and in-silico approach

A Dutta, MA Hossain, PD Somadder, MA Moli… - Diabetes & Metabolic …, 2024 - Elsevier
Aims The main objective of the current study is to investigate the pathways and therapeutic
targets linked to stevioside in the management of T2D using computational approaches …

Tangeretin exerts and modulates the anxiolytic effects of the GABAkine drugs diazepam and flumazenil in mice: Molecular interventions through animal behavior and …

Z Husain, M Saifiuzzaman, MS Bhuia, J Ferdous… - Food Bioscience, 2024 - Elsevier
The citrus peel flavonoid tangeretin (TAN) has diverse biological activities, including
antioxidant, anti-inflammatory, anti-tumor, hepatoprotective, and neuroprotective effects. This …