The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

Chimeric antigen receptor T (CAR-T) cell therapy represents a major breakthrough in cancer
treatment, and it has achieved unprecedented success in hematological malignancies …

Over the last decade, the survival outcome of patients with multiple myeloma (MM) has been
substantially improved with the emergence of novel therapeutic agents, such as proteasome …

The potential of cancer immunotherapy relies on the mobilization of immune cells capable of
producing antitumour cytokines and effectively killing tumour cells. These are major …

With the promise of T cell-based therapy for cancer finally becoming reality, this Review
focuses on the less-studied γδ T cell lineage and its diverse responses to tumours. γδ T cells …

Most studies on the immunotherapeutic potential of T cells have focused on CD8 and CD4 T
cells that recognize peptide antigens (Ag) presented by polymorphic major histocompatibility …

The unique features of gamma-delta (γδ) T cells, related to their antigen recognition
capacity, their tissue tropism, and their cytotoxic function, make these cells ideal candidates …

γδ T lymphocytes represent∼ 1% of human peripheral blood mononuclear cells and even
more cells in most tissues of vertebrates. Although they have important anticancer functions …

A growing number of studies have shown that γδ T cells play a pivotal role in mediating the
clearance of tumors and pathogen-infected cells with their potent cytotoxic, cytolytic, and …

Chimeric antigen receptor T-cell (CAR-T) therapy has been prosperous in the treatment of
patients with various types of relapsed/refractory (R/R) B-cell malignancies including diffuse …