Nanotechnology-based mucoadhesive and mucus-penetrating drug-delivery systems for transbuccal drug delivery

DD Desai, J Manikkath, H Lad, M Kulkarni… - …, 2023 - Taylor & Francis
Buccal drug-delivery systems present a promising approach for the drug delivery to the
buccal mucosa, addressing oral cavity-specific problems, enabling systemic delivery and …

Oral mucosa models to evaluate drug permeability

E Mazzinelli, I Favuzzi, A Arcovito, R Castagnola… - Pharmaceutics, 2023 - mdpi.com
Due to its numerous advantages, such as excellent drug accessibility, rapid absorption, and
bypass of first-pass metabolism, the route of drug administration that involves crossing the …

Dually Active Apigenin-Loaded Nanostructured Lipid Carriers for Cancer Treatment

L Bonilla-Vidal, M Świtalska, M Espina… - International journal …, 2023 - Taylor & Francis
Purpose Cancer is one of the major causes of death worldwide affecting more than 19
million people. Traditional cancer therapies have many adverse effects and often result in …

Synthesis and biological applications of nanocomposite hydrogels based on the methacrylation of hydroxypropyl methylcellulose and lignin loaded with alpha-pinene

Z Zarei, M Kharaziha, F Karimzadeh, E Khadem - Carbohydrate Polymers, 2024 - Elsevier
Oral conditions, such as recurrent aphthous stomatitis, are chronic inflammatory disorders
that significantly affect the life quality. This study aims to develop a novel buccal …

Lipid nanoparticle-based formulations for high-performance dentistry applications

I Mutreja, D Kumar, A Kaushik… - Journal of Materials …, 2023 - pubs.rsc.org
In the growing field of dentistry research, there is significant scope for investigating novel
and high-performance functional biomaterials for dental care, mainly to combat oral health …

On the Structure, Stability, and Cell Uptake of Nanostructured Lipid Carriers for Drug Delivery

R Jeitler, C Glader, G König, J Kaplan… - Molecular …, 2024 - ACS Publications
The efficacy of nanostructured lipid carriers (NLC) for drug delivery strongly depends on
their stability and cell uptake. Both properties are governed by their compositions and …

Lipid nanoparticles for lutein encapsulation and delivery

AD Shirokikh, YA Guruleva, EA Marinets, MY Koroleva - Colloid Journal, 2023 - Springer
Recently, lipid nanoparticles have been intensively studied as carriers of lipophilic drugs. In
this work, we have studied the stability of nanoemulsions with paraffin oil, solid lipid …

[HTML][HTML] Investigation of nanostructured lipid carriers for fast intracellular localization screening using the Echo liquid handler

C Glader, R Jeitler, S Stanzer, N Harbusch… - International Journal of …, 2024 - Elsevier
In the field of precision medicine, therapy is optimized individually for each patient,
enhancing efficacy while reducing side effects. This involves the identification of promising …

Combined photodynamic therapy and hollow microneedle approach for effective non-invasive delivery of hypericin for the management of imiquimod-induced …

M Zewail, H Abbas, N El Sayed… - Journal of Drug …, 2024 - Taylor & Francis
Background Conventional topical psoriasis treatments suffer from limited delivery to affected
areas and skin irritation due to high local drug concentration. Purpose This study aims to …

[HTML][HTML] Establishment of a semi-continuous nano-production line using the Microfluidizer® technology for the fabrication of lipid-based nanoparticles part 1 …

C Glader, R Jeitler, Y Wang, C Tetyczka, M Zettl… - European Journal of …, 2024 - Elsevier
A variety of strategies for producing high-quality nanoparticles have been reported in recent
years. Batch-based bottom-up and top-down technologies are generally the most efficient …