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Causes and consequences of centrosome abnormalities in cancer
Centrosome amplification is a hallmark of cancer. However, despite significant progress in
recent years, we are still far from understanding how centrosome amplification affects …
recent years, we are still far from understanding how centrosome amplification affects …
[HTML][HTML] Mechanisms of oncogenesis by HTLV-1 Tax
The human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …
The HTLV-1 tax interactome
M Boxus, JC Twizere, S Legros, JF Dewulf, R Kettmann… - Retrovirology, 2008 - Springer
The Tax1 oncoprotein encoded by Human T-lymphotropic virus type I is a major determinant
of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling …
of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling …
How I treat adult T-cell leukemia/lymphoma
Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy of mature activated T
cells caused by human T-cell lymphotropic virus type I. ATL carries a bad prognosis …
cells caused by human T-cell lymphotropic virus type I. ATL carries a bad prognosis …
[HTML][HTML] Molecular mechanisms of HTLV-1 cell-to-cell transmission
C Gross, AK Thoma-Kress - Viruses, 2016 - mdpi.com
The tumorvirus human T-cell lymphotropic virus type 1 (HTLV-1), a member of the delta-
retrovirus family, is transmitted via cell-containing body fluids such as blood products …
retrovirus family, is transmitted via cell-containing body fluids such as blood products …
HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways
R Currer, R Van Duyne, E Jaworski, I Guendel… - Frontiers in …, 2012 - frontiersin.org
Human T-cell lymphotropic virus type 1 (HTLV-1) has been identified as the causative agent
of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic …
of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic …
Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer
AJ Wiecek, SJ Cutty, D Kornai, M Parreno-Centeno… - Genome Biology, 2023 - Springer
Background Therapy resistance in cancer is often driven by a subpopulation of cells that are
temporarily arrested in a non-proliferative G0 state, which is difficult to capture and whose …
temporarily arrested in a non-proliferative G0 state, which is difficult to capture and whose …
[HTML][HTML] HTLV-1 infection and pathogenesis: new insights from cellular and animal models
Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …
models have provided invaluable contributions in the knowledge of viral infection …
Primary cells from patients with adult T cell leukemia/lymphoma depend on HTLV-1 Tax expression for NF-κB activation and survival
Adult T cell leukemia/lymphoma (ATL) is an aggressive malignancy secondary to chronic
infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax …
infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax …
Novel treatments of adult T cell leukemia lymphoma
H El Hajj, K Tsukasaki, M Cheminant… - Frontiers in …, 2020 - frontiersin.org
Adult T cell leukemia-lymphoma (ATL) is an aggressive malignancy secondary to chronic
infection with the human T cell leukemia virus type I (HTLV-I) retrovirus. ATL carries a dismal …
infection with the human T cell leukemia virus type I (HTLV-I) retrovirus. ATL carries a dismal …