Early adolescent substance use dramatically increases the risk of lifelong substance use
disorder (SUD). An adolescent sensitive period evolved to allow the development of risk …

Drug use is a choice with immediate positive outcomes, but long-term negative
consequences. Thus, the repeated use of drugs in the face of negative consequences …

Cocaine users consistently display cognitive impairments. However, it is still unknown
whether these impairments are cocaine-induced and if they are reversible. Therefore, we …

Disruptions to inhibitory control are believed to contribute to multiple aspects of drug abuse,
from preexisting vulnerability in at-risk individuals, through escalation to dependence, to …

Chronic cocaine users consistently display neurochemical and functional alterations in brain
areas involved in social cognition (eg medial and orbitofrontal cortex). Although social …

Background The predominant view of chronic cocaine use maintains that it causes a broad
range of cognitive deficits. However, concerns about the possibly deleterious impact of …

Based on their pharmacological properties, psychoactive drugs are supposed to take control
of the natural reward system to finally drive compulsory drug seeking and consumption …

BackgroundIndividuals with cocaine and gambling addictions exhibit cognitive flexibility
deficits that may underlie persistence of harmful behaviours. AimsWe investigated the neural …

Heavy use of drugs impacts of the daily activities of individuals in these activities. Several
groups of investigators have indeed documented changes in cognitive performance by …

BackgroundMaladaptive decision-making is assumed to be a core feature of cocaine
addiction. Indeed, numerous studies have reported deficits in non-social decision-making …