The role of ROS in tumour development and progression
EC Cheung, KH Vousden - Nature Reviews Cancer, 2022 - nature.com
Eukaryotic cells have developed complex systems to regulate the production and response
to reactive oxygen species (ROS). Different ROS control diverse aspects of cell behaviour …
to reactive oxygen species (ROS). Different ROS control diverse aspects of cell behaviour …
Targeting cancer metabolism in the era of precision oncology
One hundred years have passed since Warburg discovered alterations in cancer
metabolism, more than 70 years since Sidney Farber introduced anti-folates that …
metabolism, more than 70 years since Sidney Farber introduced anti-folates that …
Cancer metabolism: looking forward
Tumour initiation and progression requires the metabolic reprogramming of cancer cells.
Cancer cells autonomously alter their flux through various metabolic pathways in order to …
Cancer cells autonomously alter their flux through various metabolic pathways in order to …
Metabolomics in cancer research and emerging applications in clinical oncology
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism
I Elia, MC Haigis - Nature metabolism, 2021 - nature.com
Metabolic transformation is a hallmark of cancer and a critical target for cancer therapy.
Cancer metabolism and behaviour are regulated by cell-intrinsic factors as well as …
Cancer metabolism and behaviour are regulated by cell-intrinsic factors as well as …
Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia
Glucose dependency of cancer cells can be targeted with a high-fat, low-carbohydrate
ketogenic diet (KD). However, in IL-6-producing cancers, suppression of the hepatic …
ketogenic diet (KD). However, in IL-6-producing cancers, suppression of the hepatic …
Emerging therapies in cancer metabolism
Y ** dietary interventions as therapy for cancer
Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic
alterations and degree of interaction with systemic hormones and metabolites. These …
alterations and degree of interaction with systemic hormones and metabolites. These …