Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024‏ - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022‏ - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application

X Zhao, J Liu, J Fan, H Chao, X Peng - Chemical Society Reviews, 2021‏ - pubs.rsc.org
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …

Activity‐based NIR enzyme fluorescent probes for the diagnosis of tumors and image‐guided surgery

H Li, D Kim, Q Yao, H Ge, J Chung, J Fan… - Angewandte …, 2021‏ - Wiley Online Library
Near‐infrared (NIR) activatable fluorescent probes have been considered to be the effective
edge tools for the investigation of cell biology and disease diagnosis because of their …

Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019‏ - pubs.rsc.org
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Small molecule as fluorescent probes for monitoring intracellular enzymatic transformations

H Singh, K Tiwari, R Tiwari, SK Pramanik… - Chemical …, 2019‏ - ACS Publications
All cellular processes are the results of synchronized actions of several intracellular
biochemical pathways. Recent emphasis is to visualize such pathways using appropriate …

Pyrene-Based AIEE Active Nanoprobe for Zn2+ and Tyrosine Detection Demonstrated by DFT, Bioimaging, and Organic Thin-Film Transistor

M Shellaiah, YT Chen, N Thirumalaivasan… - … Applied Materials & …, 2021‏ - ACS Publications
The development of aggregation-induced emission enhancement (AIEE) active nanoprobes
without any synthetic complication for solution-state and organic thin-film transistor (OTFT) …

Dual-locked near-infrared fluorescent probes for precise detection of melanoma via hydrogen peroxide–tyrosinase cascade activation

H Peng, T Wang, G Li, J Huang, Q Yuan - Analytical Chemistry, 2021‏ - ACS Publications
Activity-based near-infrared (NIR) fluorescent probes provide powerful tools for diagnosis of
diseases. However, most of these probes suffer from low specificity due to “off-target” …

Monitoring acetylcholinesterase level changes under oxidative stress through ESIPT-ICT-based near-infrared fluorescent probe

X Wei, T Zhu, Y Ma, J Sun, G Zheng, T Ma… - Sensors and Actuators B …, 2023‏ - Elsevier
Oxidative stress plays an important role in pathology, and contributes to a variety of
diseases, including inflammation, neurodegenerative diseases, and cancer. Research …

Cancer-targeting and viscosity-activatable near-infrared fluorescent probe for precise cancer cell imaging

M Qian, Y Ye, TB Ren, B **ong, L Yuan… - Analytical …, 2024‏ - ACS Publications
Small-molecule fluorescent probes have emerged as potential tools for cancer cell imaging-
based diagnostic and therapeutic applications, but their limited selectivity and poor imaging …