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Physical models of collective cell migration
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
Motility-induced phase separation
Self-propelled particles include both self-phoretic synthetic colloids and various
microorganisms. By continually consuming energy, they bypass the laws of equilibrium …
microorganisms. By continually consuming energy, they bypass the laws of equilibrium …
Motility-driven glass and jamming transitions in biological tissues
Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …
development and cancer metastasis, and recent experiments suggest that these tissues …
Emergent behavior in active colloids
Active colloids are microscopic particles, which self-propel through viscous fluids by
converting energy extracted from their environment into directed motion. We first explain …
converting energy extracted from their environment into directed motion. We first explain …
Unjamming and cell shape in the asthmatic airway epithelium
From coffee beans flowing in a chute to cells remodelling in a living tissue, a wide variety of
close-packed collective systems—both inert and living—have the potential to jam. The …
close-packed collective systems—both inert and living—have the potential to jam. The …
Self-enhanced mobility enables vortex pattern formation in living matter
Ranging from subcellular organelle biogenesis to embryo development, the formation of self-
organized structures is a hallmark of living systems. Whereas the emergence of ordered …
organized structures is a hallmark of living systems. Whereas the emergence of ordered …
Active gel physics
The mechanical behaviour of cells is largely controlled by a structure that is fundamentally
out of thermodynamic equilibrium: a network of crosslinked filaments subjected to the action …
out of thermodynamic equilibrium: a network of crosslinked filaments subjected to the action …
A density-independent rigidity transition in biological tissues
Cell migration is important in many biological processes, including embryonic development,
cancer metastasis and wound healing. In these tissues, a cell's motion is often strongly …
cancer metastasis and wound healing. In these tissues, a cell's motion is often strongly …
Hydrodynamics of soft active matter
This review summarizes theoretical progress in the field of active matter, placing it in the
context of recent experiments. This approach offers a unified framework for the mechanical …
context of recent experiments. This approach offers a unified framework for the mechanical …
In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …