Brain atrophy in Alzheimer's disease and aging

L Pini, M Pievani, M Bocchetta, D Altomare… - Ageing research …, 2016 - Elsevier
Thanks to its safety and accessibility, magnetic resonance imaging (MRI) is extensively used
in clinical routine and research field, largely contributing to our understanding of the …

The microbiota–gut–brain axis in Alzheimer's disease: a review of taxonomic alterations and potential avenues for interventions

ER Murray, M Kemp, TT Nguyen - Archives of Clinical …, 2022 - academic.oup.com
Objective The gut microbiome is a complex community of microorganisms that inhabit the
gastrointestinal tract. The microbiota–gut–brain axis encompasses a bidirectional …

A probabilistic atlas of the human thalamic nuclei combining ex vivo MRI and histology

JE Iglesias, R Insausti, G Lerma-Usabiaga… - Neuroimage, 2018 - Elsevier
The human thalamus is a brain structure that comprises numerous, highly specific nuclei.
Since these nuclei are known to have different functions and to be connected to different …

Deep residual learning for neuroimaging: an application to predict progression to Alzheimer's disease

A Abrol, M Bhattarai, A Fedorov, Y Du, S Plis… - Journal of neuroscience …, 2020 - Elsevier
Background The unparalleled performance of deep learning approaches in generic image
processing has motivated its extension to neuroimaging data. These approaches learn …

Prediction and classification of Alzheimer disease based on quantification of MRI deformation

X Long, L Chen, C Jiang, L Zhang… - PloS one, 2017 - journals.plos.org
Detecting early morphological changes in the brain and making early diagnosis are
important for Alzheimer's disease (AD). High resolution magnetic resonance imaging can be …

Four distinct subtypes of Alzheimer's disease based on resting-state connectivity biomarkers

P Chen, H Yao, BM Tijms, P Wang, D Wang, C Song… - Biological …, 2023 - Elsevier
Background Alzheimer's disease (AD) is a neurodegenerative disorder with significant
heterogeneity. Different AD phenotypes may be associated with specific brain network …

The insulin resistance by triglyceride glucose index and risk for dementia: population-based study

S Hong, K Han, CY Park - Alzheimer's research & therapy, 2021 - Springer
Background Insulin resistance is suggested to have negative effects on cognition; however,
results from large population studies are lacking. In this study, the potential relationships …

Associations of Alzheimer's disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration

MS Tan, YX Yang, W Xu, HF Wang, L Tan… - Alzheimer's Research & …, 2021 - Springer
Background Genome-wide association studies have identified more than 30 Alzheimer's
disease (AD) risk genes, although the detailed mechanism through which all these genes …

A systematic review of longitudinal studies which measure Alzheimer's disease biomarkers

E Lawrence, C Vegvari, A Ower… - Journal of …, 2017 - content.iospress.com
Alzheimer's disease (AD) is a progressive and fatal neurodegenerative disease, with no
effective treatment or cure. A gold standard therapy would be treatment to slow or halt …

Are there differences in brain morphology according to handedness?

H Jang, JY Lee, KI Lee, KM Park - Brain and behavior, 2017 - Wiley Online Library
Objective This study aimed to investigate the differences in brain morphology according to
handedness. Materials and Methods Forty‐two healthy subjects were enrolled (21 right …