Beyond t test and ANOVA: applications of mixed-effects models for more rigorous statistical analysis in neuroscience research

Z Yu, M Guindani, SF Grieco, L Chen, TC Holmes, X Xu - Neuron, 2022 - cell.com
In basic neuroscience research, data are often clustered or collected with repeated
measures, hence correlated. The most widely used methods such as t test and ANOVA do …

[HTML][HTML] The world cancer research fund/American institute for cancer research third expert report on diet, nutrition, physical activity, and cancer: impact and future …

SK Clinton, EL Giovannucci, SD Hursting - The Journal of nutrition, 2020 - Elsevier
ABSTRACT The Third Expert Report on Diet, Nutrition, Physical Activity, and Cancer: A
Global Perspective by the World Cancer Research Fund (WCRF) and the American Institute …

[HTML][HTML] AI for life: Trends in artificial intelligence for biotechnology

A Holzinger, K Keiblinger, P Holub, K Zatloukal… - New biotechnology, 2023 - Elsevier
Due to popular successes (eg, ChatGPT) Artificial Intelligence (AI) is on everyone's lips
today. When advances in biotechnology are combined with advances in AI unprecedented …

Investigating the replicability of preclinical cancer biology

TM Errington, M Mathur, CK Soderberg, A Denis… - elife, 2021 - elifesciences.org
Replicability is an important feature of scientific research, but aspects of contemporary
research culture, such as an emphasis on novelty, can make replicability seem less …

Challenges for assessing replicability in preclinical cancer biology

TM Errington, A Denis, N Perfito, E Iorns, BA Nosek - elife, 2021 - elifesciences.org
We conducted the Reproducibility Project: Cancer Biology to investigate the replicability of
preclinical research in cancer biology. The initial aim of the project was to repeat 193 …

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

N Percie du Sert, V Hurst, A Ahluwalia… - Journal of Cerebral …, 2020 - journals.sagepub.com
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal
Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve …

[HTML][HTML] Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

NP Du Sert, A Ahluwalia, S Alam, MT Avey… - PLoS …, 2020 - journals.plos.org
Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

How to measure and evaluate binding affinities

I Jarmoskaite, I AlSadhan, PP Vaidyanathan… - Elife, 2020 - elifesciences.org
Quantitative measurements of biomolecule associations are central to biological
understanding and are needed to build and test predictive and mechanistic models. Given …

A critical review on the potential impacts of neonicotinoid insecticide use: current knowledge of environmental fate, toxicity, and implications for human health

DA Thompson, HJ Lehmler, DW Kolpin… - … Science: Processes & …, 2020 - pubs.rsc.org
Neonicotinoid insecticides are widely used in both urban and agricultural settings around
the world. Historically, neonicotinoid insecticides have been viewed as ideal replacements …

Minimum reporting standards for in vivo magnetic resonance spectroscopy (MRSinMRS): experts' consensus recommendations

A Lin, O Andronesi, W Bogner, IY Choi… - NMR in …, 2021 - Wiley Online Library
The translation of MRS to clinical practice has been impeded by the lack of technical
standardization. There are multiple methods of acquisition, post‐processing, and analysis …