Protein aggregation has been recognized as one of the major challenges in the
development and commercialization of successful protein-based drug products because of …

Solid dosage forms of biopharmaceuticals such as therapeutic proteins could provide
enhanced bioavailability, improved storage stability, as well as expanded alternatives to …

Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …

Spray-drying is an inherently continuous and well-established industrial drying process. It
can accelerate manufacturing of biopharmaceuticals and vaccine products, resulting in both …

Background Pulmonary route is an attractive target for both systemic and local drug delivery,
with the advantages of a large surface area, rich blood supply, and absence of first-pass …

For inhalation drug delivery, amorphous powder formulations offer the benefits of increased
bioavailability for poorly soluble drugs, improved biochemical stability for biologics, and …

The global market of pharmaceutical biologics has expanded significantly during the last few
decades. Currently, pharmaceutical biologic products constitute an indispensable part of the …

Protein pharmaceuticals have become a significant class of marketed drug products and are
expected to grow steadily over the next decade. Development of a commercial protein …

Respiratory diseases are among the leading causes of morbidity and mortality worldwide.
Innovations in biochemical engineering and understanding of the pathophysiology of …

The clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-
associated protein 9 (CRISPR/Cas9) system has significant therapeutic potentials for lung …