Deciphering Proteoform Landscape of Mammary Carcinoma by Top-Down Proteomics

SJ Knott, T Tucholski, H Josyer, D Inman… - Journal of Proteome …, 2025 - ACS Publications
Defining the proteoform landscape of breast cancer can provide unique insights into the
signaling pathways driving disease progression. While bottom-up proteomics has been …

Characterization of Complex Proteoform Mixtures by Online Nanoflow Ion-Exchange Chromatography-Native Mass Spectrometry

Z Zhai, D Mavridou, M Damian, FG Mutti… - Analytical …, 2024 - ACS Publications
The characterization of proteins and complexes in biological systems is essential to
establish their critical properties and to understand their unique functions in a plethora of …

Practically complementary size exclusion chromatography and reversed-phase liquid chromatography for the preparative separation of structurally similar flavone-C …

J Dang, Y Lv, AMA El-Aty, G Li - Journal of Chromatography A, 2025 - Elsevier
In this study, a practicably complementary size exclusion chromatography and reversed-
phase liquid chromatography method was constructed and applied to efficiently separate …

基于质谱的单细胞蛋白质组学分析策略与应用

**国星, 魏星, 陈明丽, 王建华 - 分析测试学报, 2024 - fxcsxb.com
细胞间异质性已被证明存在于各类生物体及其发育过程中. 传统对于群体细胞的测量所得到的
**均结果往往无法用于单细胞异质性的分析, 因此开展单细胞水**的研究对于单个细胞的生理 …

Strategies and Applications of Single Cell Proteomics Analysis Based on Mass Spectrometry

LI Guo-xing, WEI **ng, C Ming-li, W Jian-hua - zggx, 2024 - fxcsxb.com
Intercellular heterogeneity has been demonstrated to exist in various organisms and their
development. Conventionally, the average results obtained from measurements of …