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Lipid-based nanoparticles for drug/gene delivery: an overview of the production techniques and difficulties encountered in their industrial development
Over the past decade, the therapeutic potential of nanomaterials as novel drug delivery
systems complementing conventional pharmacology has been widely acknowledged …
systems complementing conventional pharmacology has been widely acknowledged …
Cell membrane-coated nanoparticles: a novel multifunctional biomimetic drug delivery system
H Liu, YY Su, XC Jiang, JQ Gao - Drug Delivery and Translational …, 2023 - Springer
Recently, nanoparticle-based drug delivery systems have been widely used for the
treatment, prevention, and detection of diseases. Improving the targeted delivery ability of …
treatment, prevention, and detection of diseases. Improving the targeted delivery ability of …
Advances and limitations of drug delivery systems formulated as eye drops
Topical instillation of eye drops remains the most common and easiest route of ocular drug
administration, representing the treatment of choice for many ocular diseases. Nevertheless …
administration, representing the treatment of choice for many ocular diseases. Nevertheless …
Stability characterization for pharmaceutical liposome product development with focus on regulatory considerations: An update
Liposomes have several advantages, such as the ability to be employed as a carrier/vehicle
for a variety of drug molecules and at the same time they are safe and biodegradable. In the …
for a variety of drug molecules and at the same time they are safe and biodegradable. In the …
Nanoparticle-based drug delivery systems: a commercial and regulatory outlook as the field matures
Introduction: Nanomedicine has emerged as a major field of academic research with direct
impact on human health. While a first generation of products has been successfully …
impact on human health. While a first generation of products has been successfully …
BCS class IV drugs: Highly notorious candidates for formulation development
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …
exhibit many characteristics that are problematic for effective oral and per oral delivery …
In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles
Increasing biomedical applications of iron oxide nanoparticles (IONPs) in academic and
commercial settings have alarmed the scientific community about the safety and assessment …
commercial settings have alarmed the scientific community about the safety and assessment …
Sterilization of hydrogels for biomedical applications: A review
Despite the beneficial properties and outstanding potential of hydrogels for biomedical
applications, several unmet challenges must be overcome, especially regarding to their …
applications, several unmet challenges must be overcome, especially regarding to their …
Polymer-based carriers for ophthalmic drug delivery
Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …
Endotoxin contamination: a key element in the interpretation of nanosafety studies
Y Li, D Boraschi - Nanomedicine, 2016 - Taylor & Francis
The study of toxicity and potential risks of engineered nanoparticles is of particular
importance in nanomedicine. Endotoxin, a common contaminant of bacterial origin, has …
importance in nanomedicine. Endotoxin, a common contaminant of bacterial origin, has …