The role of associative fear and avoidance learning in anxiety disorders: Gaps and directions for future research

A Pittig, M Treanor, RT LeBeau, MG Craske - … & Biobehavioral Reviews, 2018 - Elsevier
Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

[HTML][HTML] Fear in the context of pain: Lessons learned from 100 years of fear conditioning research

A Meulders - Behaviour research and therapy, 2020 - Elsevier
Human fear conditioning research since Watson's case study on “Little Albert” has vastly
evolved and its impact today is reaching far beyond phobic anxiety. This review focuses on …

Change of threat expectancy as mechanism of exposure-based psychotherapy for anxiety disorders: Evidence from 8,484 exposure exercises of 605 patients

A Pittig, I Heinig, S Goerigk, J Richter… - Clinical …, 2023 - journals.sagepub.com
Individual responses to behavioral treatment of anxiety disorders vary considerably, which
requires a better understanding of underlying processes. In this study, we examined the …

Memories are not written in stone: Re-writing fear memories by means of non-invasive brain stimulation and optogenetic manipulations

S Borgomaneri, S Battaglia, G Sciamanna… - Neuroscience & …, 2021 - Elsevier
The acquisition of fear associative memory requires brain processes of coordinated neural
activity within the amygdala, prefrontal cortex (PFC), hippocampus, thalamus and brainstem …

[HTML][HTML] The role of serotonin in fear learning and memory: A systematic review of human studies

F Tortora, AL Hadipour, S Battaglia, A Falzone… - Brain sciences, 2023 - mdpi.com
Fear is characterized by distinct behavioral and physiological responses that are essential
for the survival of the human species. Fear conditioning (FC) serves as a valuable model for …

Better safe than sorry: A common signature of general vulnerability for psychopathology

O Van den Bergh, J Brosschot… - Perspectives on …, 2021 - journals.sagepub.com
Several labels, such as neuroticism, negative emotionality, and dispositional negativity,
indicate a broad dimension of psychopathology. However, largely separate, often disorder …

[HTML][HTML] Avoidance and its bi-directional relationship with conditioned fear: Mechanisms, moderators, and clinical implications

A Pittig, AHK Wong, VM Glück, JM Boschet - Behaviour Research and …, 2020 - Elsevier
Fear motivates different types of defensive behaviors. These behaviors are, however, not
mere byproducts of fear. In this review, we highlight a bi-directional relationship between …

Navigating the garden of forking paths for data exclusions in fear conditioning research

TB Lonsdorf, M Klingelhöfer-Jens, M Andreatta… - Elife, 2019 - elifesciences.org
In this report, we illustrate the considerable impact of researcher degrees of freedom with
respect to exclusion of participants in paradigms with a learning element. We illustrate this …

[HTML][HTML] The role of intolerance of uncertainty in classical threat conditioning: Recent developments and directions for future research

J Morriss, DV Zuj, G Mertens - International Journal of Psychophysiology, 2021 - Elsevier
Intolerance of uncertainty (IU), the tendency to find uncertainty aversive, is an important
transdiagnostic dimension in mental health disorders. Over the last decade, there has been …

A current learning theory approach to the etiology and course of anxiety and related disorders

RE Zinbarg, AL Williams… - Annual Review of Clinical …, 2022 - annualreviews.org
The authors describe how contemporary learning theory and research provide the basis for
models of the etiology and maintenance of anxiety and related disorders. They argue that …