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Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …
worldwide and is often associated with aspects of metabolic syndrome. Despite its …
Role of oxidative stress in the pathogenesis of non-alcoholic fatty liver disease: implications for prevention and therapy
Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflammatory
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …
Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …
disease worldwide and is strongly associated with the presence of oxidative stress …
Pathogenesis and treatment of non-alcoholic steatohepatitis and its fibrosis
KC Lee, PS Wu, HC Lin - Clinical and molecular hepatology, 2022 - pmc.ncbi.nlm.nih.gov
The initial presentation of non-alcoholic steatohepatitis (NASH) is hepatic steatosis. The
dysfunction of lipid metabolism within hepatocytes caused by genetic factors, diet, and …
dysfunction of lipid metabolism within hepatocytes caused by genetic factors, diet, and …
Role of insulin resistance in MAFLD
Y Sakurai, N Kubota, T Yamauchi… - International journal of …, 2021 - mdpi.com
Many studies have reported that metabolic dysfunction is closely involved in the complex
mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), which …
mechanism underlying the development of non-alcoholic fatty liver disease (NAFLD), which …
Compromised hepatic mitochondrial fatty acid oxidation and reduced markers of mitochondrial turnover in human NAFLD
Background and Aims NAFLD and its more‐advanced form, steatohepatitis (NASH), is
associated with obesity and is an independent risk factor for cardiovascular, liver‐related …
associated with obesity and is an independent risk factor for cardiovascular, liver‐related …
Metabolic and signaling roles of ketone bodies in health and disease
Ketone bodies play significant roles in organismal energy homeostasis, serving as oxidative
fuels, modulators of redox potential, lipogenic precursors, and signals, primarily during …
fuels, modulators of redox potential, lipogenic precursors, and signals, primarily during …
Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA
Abstract Changes in mitochondrial morphology are associated with nutrient utilization, but
the precise causalities and the underlying mechanisms remain unknown. Here, using …
the precise causalities and the underlying mechanisms remain unknown. Here, using …
The liver as an endocrine organ—linking NAFLD and insulin resistance
The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …
[HTML][HTML] Role of NAD+ in regulating cellular and metabolic signaling pathways
Background Nicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in
every living cell, is involved in a myriad of metabolic processes associated with cellular …
every living cell, is involved in a myriad of metabolic processes associated with cellular …