Proton pump inhibitors (PPIs) have been available for over three decades and are among
the most commonly prescribed medications. They are effective in treating a variety of gastric …

Importance The clinical decision to initiate bisphosphonate therapy for the treatment of
osteoporosis requires balancing shorter-term harms and burdens (eg, gastroesophageal …

Introduction: Osteoporosis is a disease that has spread worldwide and has become a
relevant public health problem. Over the last 2 decades, a number of drugs have been …

Study Design. A population-based retrospective cohort study. Objective. The aim of this
study was to examine risk factors for long-term opioid use following lumbar spinal fusion …

Although oral bisphosphonates (BP) are commonly used, there is conflicting evidence for
their safety in the elderly. Safety concerns might trump BP use in older patients with complex …

Background Alendronate is used to treat Paget's bone disease, glucocorticoid‐induced
osteoporosis, and postmenopausal osteoporosis because it suppresses osteoclast activity to …

Purpose A large proportion of women with osteoporosis do not comply with current
osteoporosis therapies, resulting in diminished therapeutic effect. Noncompliance may be …

Background and aims Clinical data regarding alendronate jelly are limited. We compared
the efficacy and safety of once‐weekly alendronate oral jelly with once‐weekly alendronate …

Background: Recent studies show that adults with intellectual disabilities (ID) have high
incidence of major osteoporotic fracture, especially hip fracture. In those≥ 50 years, women …

Advances in pharmacotherapy have greatly contributed to an increased life expectancy of
the adult population. As a result, an ever increasing proportion of the global population now …