Thousand and one kinases (TAOKs) are members of the MAP kinase kinase kinase
(MAP3K) family. Three members of this subfamily, TAOK1, 2, and 3, have been identified in …

Store operated calcium entry (SOCE) is a principal cellular process by which cells regulate
basal calcium, refill intracellular Ca 2+ stores, and execute a wide range of specialized …

Context Adrenarche refers to the rise of dehydroepiandrosterone sulfate (DHEA-S)
associated with the development of a functional adrenal zona reticularis. Clinical features of …

Abstract Magnesium (Mg 2+) plays an important role in various cellular functions such as
protein synthesis, DNA stability, energy metabolism, enzyme and channel activities, and …

The transcriptional activity of the androgen receptor (AR) is not only critical for the normal
development and function of the prostate but also pivotal to the onset and progression of …

In mammals, germ cell differentiation is initiated in the Primordial Germ Cells (PGCs) during
fetal development. Prenatal exposure to environmental toxicants such as endocrine …

Diffuse large B-cell lymphoma (DLBCL), an invasive lymphoma with substantial
heterogeneity, can be mainly categorised into germinal centre B-cell-like (GCB) and non …

Background There is no cure for castration-recurrent prostate cancer (CRPC) and the
mechanisms underlying this stage of the disease are unknown. Methods We analyzed the …

If and how obesity and elevated androgens in women with polycystic ovary syndrome
(PCOS) affect their offspring's psychiatric health is unclear. Using data from Swedish …

The treatment of castration-resistant prostate cancer (CRPC) still faces many challenges.
Docetaxel is a chemotherapeutic drug commonly used in CRPC patients. However …