Achalasia is a rare disorder of the oesophageal smooth muscle characterized by impaired
relaxation of the lower oesophageal sphincter (LES) and absent or spastic contractions in …

Dysphagia is a common symptom with significant impact on quality of life. Our diagnostic
armamentarium was primarily limited to endoscopy and barium esophagram until the advent …

METHODS: Five hundred thirty-nine adult patients who completed FLIP and HRM with a
conclusive CCv4. 0 diagnosis were included in the primary analysis. Thirty-five …

Esophageal hypomotility disorders manifest with abnormal esophageal body contraction
vigor, breaks in peristaltic integrity, or failure of peristalsis in the context of normal lower …

Background & Aims This study aimed to assess the accuracy of functional luminal imaging
probe (FLIP) panometry to detect esophagogastric junction (EGJ) obstruction assigned by …

Eosinophilic esophagitis (EoE) is a chronic type 2 inflammation-mediated disease
characterized by an eosinophil-predominant inflammation of the esophagus and symptoms …

Eosinophilic esophagitis (EoE) represents a growing cause of chronic esophageal morbidity
whose incidence and prevalence are increasing rapidly. The disease is characterized by …

ABSTRACT Introduction Proton pump inhibitors (PPIs) have revolutionized the management
of acid-related disorders, representing today the mainstay treatment of these conditions …

The objective of this article is to review the evidence of abnormal gastrointestinal (GI) tract
motor functions in the context of disorders of gut–brain interaction (DGBI). These include …

Hypercontractile esophagus (HE) is a heterogeneous major motility disorder diagnosed
when≥ 20% hypercontractile peristaltic sequences (distal contractile integral> 8,000 mm …