Numerous viruses infecting bacteria and archaea encode CRISPR-Cas system inhibitors,
known as anti-CRISPR proteins (Acr). The Acrs typically are highly specific for particular …

Prokaryotes are equipped with a variety of resistance strategies to survive frequent viral
attacks or invading mobile genetic elements. Among these, CRISPR–Cas surveillance …

As part of the ongoing bacterial-phage arms race, CRISPR-Cas systems in bacteria clear
invading phages whereas anti-CRISPR proteins (Acrs) in phages inhibit CRISPR defenses …

Many bacterial and archaeal viruses encode anti-CRISPR proteins (Acrs) that specifically
inhibit CRISPR-Cas systems via various mechanisms. The majority of the Acrs are small …

Deep mutational scanning is a powerful method to explore the mutational fitness landscape
of proteins. Its adaptation to anti-CRISPR proteins, which are natural CRISPR-Cas inhibitors …

In this paper, we present a model of the bio-cyber interface for the Internet of Bio-Nano
Things application. The proposed model is inspired by the gains of integrating the Clustered …

CRISPR-Cas immune systems in bacteria and archaea protect against viral infection, which
has spurred viruses to develop dedicated inhibitors of these systems called anti-CRISPRs …

CRISPR-Cas effectors are powerful tools for genome and transcriptome targeting and
editing. Naturally, these protein–RNA complexes are part of the microbial innate immune …

Background: Clustered Regularly Interspaced Palindromic Repeats, or CRISPR, is an array
of DNA sequences found in bacteria that confer immunity against phage. Sequences within …