Resistance to tyrosine kinase inhibitors in chronic myeloid leukemia—from molecular mechanisms to clinical relevance
Simple Summary Chronic myeloid leukemia (CML) is a myeloproliferative neoplasia
associated with a molecular alteration, the fusion gene BCR-ABL1, that encodes the tyrosine …
associated with a molecular alteration, the fusion gene BCR-ABL1, that encodes the tyrosine …
[HTML][HTML] Ophthalmologic manifestations as the initial presentation of chronic myeloid leukemia: a review
The presentation of chronic myeloid leukemia (CML) can be variable and related to the
phase of the disease. It can manifest a wide range of symptoms and signs; ocular …
phase of the disease. It can manifest a wide range of symptoms and signs; ocular …
Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies
Small molecule therapy is a critical component of targeted anticancer treatment, with
tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic …
tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic …
Association between adherence to oral therapies in cancer patients and clinical outcome: A systematic review of the literature
Aims Adherence to therapy is a key factor in successful treatment. The aim of this systematic
review is to assess the extent to which patients with better adherence to oral therapy have …
review is to assess the extent to which patients with better adherence to oral therapy have …
Efficacy of a medication management service in improving adherence to tyrosine kinase inhibitors and clinical outcomes of patients with chronic myeloid leukaemia: a …
BK Tan, SS Chua, LC Chen, KM Chang… - Supportive Care in …, 2020 - Springer
Purpose Suboptimal adherence to tyrosine kinase inhibitors (TKIs) contributes to poor
clinical outcomes in chronic myeloid leukemia (CML). This randomised controlled trial (RCT) …
clinical outcomes in chronic myeloid leukemia (CML). This randomised controlled trial (RCT) …
Needs for information and reasons for (non) adherence in chronic myeloid leukaemia: Be aware of social activities disturbing daily routines
CCLM Boons, L Harbers, L Timmers… - European journal of …, 2018 - Wiley Online Library
Objectives To obtain insight into patients' reasons for medication (non) adherence in chronic
myeloid leukaemia (CML) and needs and wishes regarding information and communication …
myeloid leukaemia (CML) and needs and wishes regarding information and communication …
Natural history, with clinical, biochemical, and molecular characterization of classical homocystinuria in the Qatari population
Classical homocystinuria (HCU) is the most common inborn error of metabolism in Qatar,
with an incidence of 1: 1800, and is caused by the Qatari founder p. R336C mutation in the …
with an incidence of 1: 1800, and is caused by the Qatari founder p. R336C mutation in the …
Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients
Protein tyrosine phosphatase receptor gamma (PTPRG) is a member of the receptor-like
family protein tyrosine phosphatases and acts as a tumor suppressor gene in different …
family protein tyrosine phosphatases and acts as a tumor suppressor gene in different …
Assessment of dasatinib versus nilotinib as upfront therapy for chronic phase of chronic myeloid leukemia in Qatar: a cost-effectiveness analysis
Background: The economic outcome research of approved tyrosine kinase inhibitors for
treating the chronic phase of chronic myeloid leukemia in develo** is scarce. The aim of …
treating the chronic phase of chronic myeloid leukemia in develo** is scarce. The aim of …
[PDF][PDF] Imatinib mesylate adherence in chronic myeloid leukemia patients: Data from middle euphrates region of Iraq
A Mjalia, SK Abbasb - Higher education, 2021 - researchgate.net
Background: Chronic myeloid leukemia (CML) represents about one quarter of leukemia
cases in our region making it a great challenge to the health system. Aims: Since adherence …
cases in our region making it a great challenge to the health system. Aims: Since adherence …