[HTML][HTML] Epigenetic regulation in oral squamous cell carcinoma microenvironment: a comprehensive review

H Mesgari, S Esmaelian, K Nasiri, S Ghasemzadeh… - Cancers, 2023 - mdpi.com
Simple Summary This comprehensive review focuses on the role of epigenetics in oral
squamous cell carcinoma (OSCC), a prevalent type of oral cancer. The review highlights the …

[HTML][HTML] The Complex Role of Mast Cells in Head and Neck Squamous Cell Carcinoma: A Systematic Review

SE Tzorakoleftheraki, T Koletsa - Medicina, 2024 - mdpi.com
Background and Objectives: Head and neck squamous cell carcinoma (HNSCC) is a
heterogeneous malignancy influenced by various genetic and environmental factors. Mast …

Targeting polycomb repressor complex 2‐mediated bivalent promoter epigenetic silencing of secreted frizzled‐related protein 1 inhibits cholangiocarcinoma …

G Wu, Q Wang, D Wang, F **ong, W Liu… - Clinical and …, 2023 - Wiley Online Library
Background Cholangiocarcinoma (CCA) refers to a collection of malignancies that are
associated with a dismal prognosis. Currently, surgical resection is the only way to cure …

SFRP1 mediates cancer-associated fibroblasts to suppress cancer cell proliferation and migration in head and neck squamous cell carcinoma

L Dong, Y Li, X Song, C Sun, X Song - BMC cancer, 2024 - Springer
Abstract Background Cancer-associated fibroblasts (CAFs), as key cell populations in the
tumor microenvironment (TME), play a crucial role in tumor regulation. Previous studies on a …

Gene expression profiling of pancreatic ductal adenocarcinomas in response to neoadjuvant chemotherapy

S Sahni, C Nahm, MS Ahadi, L Sioson… - Cancer …, 2023 - Wiley Online Library
Aim Pancreatic ductal adenocarcinoma (PDAC) has the lowest survival rate of all major
cancers. Chemotherapy is the mainstay systemic therapy for PDAC, and chemoresistance is …

Implicating clinical utility of altered expression of PTCH1 & SMO in oral squamous cell carcinoma

HV Patel, JS Joshi, FD Shah - Journal of Molecular Histology, 2024 - Springer
Introduction Oral cancer poses a significant burden on public health in India, with higher
incidence and mortality rates. Despite advancements in treatment modalities, prognosis …

Comprehensive analysis of the clinical and prognostic significance of SFRP1 and PRKCB expression in non-small cell lung cancer: a retrospective analysis

GQ Hu, J Du, B Wang, PT Song… - European Journal of …, 2024 - journals.lww.com
Objectives Secreted frizzled-related protein 1 (SFRP1) and protein kinase CB (PRKCB)
contribute to cancer progression and angiogenesis. This study intended to detect SFRP1 …

DNA hypermethylation of tumor suppressor genes among oral squamous cell carcinoma patients: a prominent diagnostic biomarker

N Agarwal, AK Jha - Molecular Biology Reports, 2025 - Springer
Abstract Oral Squamous Cell Carcinoma is a globally revealing form of oral malignancy.
Epigenetics, which studies genetic modifications in gene expression without altering the …

Leveraging programmed cell death patterns to predict prognosis and therapeutic sensitivity in OSCC

A Wang, C Zhang, Y Wang, P Diao, J Cheng - Oral Diseases - Wiley Online Library
Objectives Intricate associations between programmed cell death (PCD) and cancer
development and treatment outcomes have been increasingly appreciated. Here, we …

Identification of crucial genes through WGCNA in the progression of clear cell renal cell carcinoma

G Li, Q Liu, X Kong, B Yang - 2024 - researchsquare.com
Background Due to the limited clinical treatment options for clear cell renal cell carcinoma
(ccRCC), this study aimed to explore the molecular mechanisms underlying ccRCC and …