Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively
affects survivals' functional outcome, response to rehabilitation and quality of life …

Acute ischaemic stroke accounts for 6.5 million deaths per year, and by 2030 will result in
the annual loss of over 200 million disability-adjusted life years globally. There have been …

Rationale: The elderly experience profound systemic responses after stroke, which
contribute to higher mortality and more severe long-term disability. Recent studies have …

The deleterious effects of chronic social isolation (SI) have been recognized for several
decades. Isolation is a major source of psychosocial stress and is associated with an …

Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of
stroke severities, from mild to substantial, can be achieved. This review describes …

Alzheimer's disease (AD) is characterized by progressive memory and neuronal loss
culminating in cognitive impairment that not only affects a person's living ability but also …

The absence of social support, or social isolation, can be stressful, leading to a suite of
physical and psychological health issues. Growing evidence suggests that disruption of the …

During pandemics, governments take drastic actions to prevent the spreading of the
disease, as seen during the present COVID-19 crisis. Sanctions of lockdown, social …

In preparation for lunar and Mars missions it is essential to consider the challenges to
human health that are posed by long-duration deep space habitation via multiple stressors …

Stroke survivors often experience social isolation. Social interaction improves quality of life
and decreases mortality after stroke. Male mice (20–25 g; C57BL/6N), all initially pair …