In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

This article presents a comprehensive review on controlled release hormonal contraceptive
systems that include transdermal patches, intravaginal rings (IVRs), intrauterine devices …

The parenteral route of administration is preferred over the oral route for treatment of many
chronic and life-threatening diseases due to better patient compliance. Long-acting …

In situ forming implants are exposed to an extracellular matrix resembling a gel rather than
aqueous solution upon subcutaneous administration. The aim of study was to develop a gel …

As a result of the low oral bioavailability of several drugs, there is a renewed interest for
parenteral administration to target their absorption directly into the blood bypassing the long …

Oral ketoconazole therapy is commonly associated with serious hepatotoxicity. Improving
ocular drug delivery could be sufficient to treat eye fungal infections. The purpose of this …

In situ forming gel (ISG) is relevant for periodontal pocket drug delivery because of its local
administration with sustained drug release. Various types of 25% w/w Eudragit®-based ISG …

In this work, we evaluated, for the first time, the antitumor effect of cannabidiol (CBD) as
monotherapy and in combination with conventional chemotherapeutics in ovarian cancer …

The metamorphosis of biodegradable polymers in biomedical applications is an auspicious
myriad of indagation. The utmost challenge in clinical conditions includes trauma, organs …

The in situ forming system has attracted attention for periodontitis treatment owing to its
sustainable drug release localisation at a periodontal pocket. Given its low aqueous …