• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Aim This clinical practice guideline for the evaluation and diagnosis of chest pain provides
recommendations and algorithms for clinicians to assess and diagnose chest pain in adult …

Health professionals are encouraged to take the ESC Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …

Cardiac computed tomography (CT) has changed rapidly since the last major guideline from
SCCT. 1 While there have been significant advances in technology, the most gratifying part …

Epidemiological and biological plausibility studies support a cause-and-effect relationship
between increased levels of physical activity or cardiorespiratory fitness and reduced …

Surveys and registries are needed to verify that real-life daily practice is in kee** with what
is recommended in the guidelines, thus completing the loop between clinical research …

With regard to a literature search for this revision, no specific strategy or formal data quality
assessment was used. Each of the 15 members of the writing group has specific expertise …

Evolving knowledge of sex-specific presentations, improved recognition of conventional and
novel risk factors, and expanded understanding of the sex-specific pathophysiology of …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted as the document was compiled through …

Traditionally, resource utilization and value considerations have been explicitly excluded
from practice guidelines and performance measures formulations, although they often are …