Minimum message length inference of secondary structure from protein coordinate data

AS Konagurthu, AM Lesk, L Allison - Bioinformatics, 2012 - academic.oup.com
Motivation: Secondary structure underpins the folding pattern and architecture of most
proteins. Accurate assignment of the secondary structure elements is therefore an important …

Mathematical and Machine Learning Approaches for Classification of Protein Secondary Structure Elements from Coordinates

A Sekmen, K Al Nasr, B Bilgin, AB Koku, C Jones - Biomolecules, 2023 - mdpi.com
Determining Secondary Structure Elements (SSEs) for any protein is crucial as an
intermediate step for experimental tertiary structure determination. SSEs are identified using …

Assigning secondary structure in proteins using AI

JV Antony, P Madhu, JP Balakrishnan… - Journal of Molecular …, 2021 - Springer
Abstract Knowledge about protein structure assignment enriches the structural and
functional understanding of proteins. Accurate and reliable structure assignment data is …

SCOT: Rethinking the classification of secondary structure elements

T Brinkjost, C Ehrt, O Koch, P Mutzel - Bioinformatics, 2020 - academic.oup.com
Motivation Secondary structure classification is one of the most important issues in structure-
based analyses due to its impact on secondary structure prediction, structural alignment and …

Machine learning approach to assign protein secondary structure elements from cα trace

M Al Sallal, W Chen, K Al Nasr - 2020 IEEE International …, 2020 - ieeexplore.ieee.org
Secondary structure elements in protein molecules refer to local sub-conformational regions
stabilized by hydrogen bonding. Secondary structure elements can be divided into helical …

Subspace modeling for classification of protein secondary structure elements from Cα trace

A Sekmen, K Al Nasr, C Jones - 2021 IEEE International …, 2021 - ieeexplore.ieee.org
This paper presents a novel subspace segmentation algorithm that models protein Cα traces
of secondary structure elements (SSEs) as a union of subspaces. For each Cα, a set of …

On representing protein folding patterns using non-linear parametric curves

P Kasarapu, MG De La Banda… - … /ACM Transactions on …, 2014 - ieeexplore.ieee.org
Proteins fold into complex three-dimensional shapes. Simplified representations of their
shapes are central to rationalise, compare, classify, and interpret protein structures …

Structure description and identification using the tableau representation of protein folding patterns

AS Konagurthu, AM Lesk - Protein Supersecondary Structures, 2013 - Springer
We have developed a concise tableau representation of protein folding patterns, based on
the order and contact patterns of elements of secondary structure: helices and strands of …

Deep Learning for Assignment of Protein Secondary Structure Elements from Cɑ Coordinates

K Al Nasr, A Sekmen, B Bilgin, C Jones… - … on Bioinformatics and …, 2021 - ieeexplore.ieee.org
This paper presents a Deep Neural network (DNN) system that uses a large set of geometric
and categorical features for classification of secondary structure elements (SSEs) in the …

Assignment of Protein Secondary Structure Elements from Cα Backbone Trace: An Ensemble of Machine Learning Approaches

K Al Nasr, A Sekmen - 2021 IEEE International Conference on …, 2021 - ieeexplore.ieee.org
Secondary structure elements in protein molecules refer to local sub-conformational regions
stabilized by hydrogen bonding. Assigning Secondary Structure Elements is crucial in …