[HTML][HTML] Next-generation molecular diagnostics: Leveraging digital technologies to enhance multiplexing in real-time PCR

L Kreitmann, L Miglietta, K Xu… - TrAC Trends in …, 2023 - Elsevier
Real-time polymerase chain reaction (qPCR) enables accurate detection and quantification
of nucleic acids and has become a fundamental tool in biological sciences, bioengineering …

A computational framework to improve cross-platform implementation of transcriptomics signatures

L Kreitmann, G D'Souza, L Miglietta, O Vito… - Ebiomedicine, 2024 - thelancet.com
The emergence of next-generation sequencing technologies and computational advances
have expanded our understanding of gene expression regulation (ie, the transcriptome) …

Droplet Encoding‐Pairing Enabled Multiplexed Digital Loop‐Mediated Isothermal Amplification for Simultaneous Quantitative Detection of Multiple Pathogens

D Cai, Y Wang, J Zou, Z Li, E Huang… - Advanced …, 2023 - Wiley Online Library
Despite the advantages of digital nucleic acid analysis (DNAA) in terms of sensitivity,
precision, and resolution, current DNAA methods commonly suffer a limitation in …

Enhancing Loop-Mediated Isothermal Amplification through Nonpowered Nanoelectric Preconcentration

NE Lee, KH Kim, Y Cho, J Kim, S Kwak, D Lee… - Analytical …, 2024 - ACS Publications
The global threat posed by the COVID-19 pandemic has catalyzed the development of point-
of-care (POC) molecular diagnostics. While loop-mediated isothermal amplification (LAMP) …

Isothermal nucleic acid amplification-based biosensors: The next generation analytical toolkit for point-of-care assay of foodborne pathogens

Y Feng, X Zhao, Q Ye, J Zou, Q Wan, F Jiang… - Trends in Food Science …, 2025 - Elsevier
Background Foodborne diseases caused by various foodborne pathogens have seriously
threatened public health and caused huge economic losses to society. Rapid, sensitive, and …

Analytical and diagnostic performance characteristics of reverse-transcriptase loop-mediated isothermal amplification assays for dengue virus serotypes 1–4: A …

P Arkell, D Mairiang, A Songjaeng… - PLOS global public …, 2023 - journals.plos.org
Dengue is a mosquito-borne disease caused by dengue virus (DENV) serotypes 1–4 which
affects 100–400 million adults and children each year. Reverse-transcriptase (RT) …

[PDF][PDF] PLOS Global Public Health

D Mairiang, A Songjaeng, K Malpartida-Cardenas… - scienceopen.com
Background Dengue is a mosquito-borne disease caused by dengue virus (DENV)
serotypes 1-4 which affects 100-400 million adults and children each year. Reverse …