Colloquium: Physical approaches to DNA sequencing and detection
M Zwolak, M Di Ventra - Reviews of Modern Physics, 2008 - APS
With the continued improvement of sequencing technologies, the prospect of genome-based
medicine is now at the forefront of scientific research. To realize this potential, however, a …
medicine is now at the forefront of scientific research. To realize this potential, however, a …
Polymer translocation: the first two decades and the recent diversification
Probably no other field of statistical physics at the borderline of soft matter and biological
physics has caused such a flurry of papers as polymer translocation since the 1994 …
physics has caused such a flurry of papers as polymer translocation since the 1994 …
Polymer translocation and nanopore sequencing: a review of advances and challenges
Various biological processes involve the translocation of macromolecules across
nanopores; these pores are basically protein channels embedded in membranes …
nanopores; these pores are basically protein channels embedded in membranes …
Influence of polymer-pore interactions on translocation
We investigate the influence of polymer-pore interactions on the translocation dynamics
using Langevin dynamics simulations. An attractive interaction can greatly improve the …
using Langevin dynamics simulations. An attractive interaction can greatly improve the …
Nanopore sensing: A physical-chemical approach
Protein nanopores have emerged as an important class of sensors for the understanding of
biophysical processes, such as molecular transport across membranes, and for the …
biophysical processes, such as molecular transport across membranes, and for the …
Langevin dynamics simulations of polymer translocation through nanopores
We investigate the dynamics of polymer translocation through a nanopore using two-
dimensional Langevin dynamics simulations. In the absence of an external driving force, we …
dimensional Langevin dynamics simulations. In the absence of an external driving force, we …
Sequence dependence of DNA translocation through a nanopore
We investigate the dynamics of DNA translocation through a nanopore using 2D Langevin
dynamics simulations, focusing on the dependence of the translocation dynamics on the …
dynamics simulations, focusing on the dependence of the translocation dynamics on the …
Modeling the separation of macromolecules: A review of current computer simulation methods
Abstract Theory and numerical simulations play a major role in the development of improved
and novel separation methods. In some cases, computer simulations predict counterintuitive …
and novel separation methods. In some cases, computer simulations predict counterintuitive …
Driven polymer translocation through nanopores: Slow-vs.-fast dynamics
We investigate the dynamics of polymer translocation through nanopores under external
driving by 3D Langevin Dynamics simulations, focusing on the scaling of the average …
driving by 3D Langevin Dynamics simulations, focusing on the scaling of the average …
Polymer translocation through a nanopore: A showcase of anomalous diffusion
The translocation dynamics of a polymer chain through a nanopore in the absence of an
external driving force is analyzed by means of scaling arguments, fractional calculus, and …
external driving force is analyzed by means of scaling arguments, fractional calculus, and …