Discovery of the luminescence of water during irradiation of radiation at a lower energy than the Cherenkov light threshold

S Yamamoto - Radiological Physics and Technology, 2021 - Springer
It is widely believed that light is not emitted in water during irradiation of radiation at energies
lower than the Cherenkov light threshold. Contrary to this consensus, we discovered that …

Prospective testing of clinical Cerenkov luminescence imaging against standard-of-care nuclear imaging for tumour location

EC Pratt, M Skubal, B Mc Larney… - Nature biomedical …, 2022 - nature.com
In oncology, the feasibility of Cerenkov luminescence imaging (CLI) has been assessed by
imaging superficial lymph nodes in a few patients undergoing diagnostic 18F-fluoro-2 …

Optical dosimetry of radiotherapy beams using Cherenkov radiation: the relationship between light emission and dose

AK Glaser, R Zhang, DJ Gladstone… - Physics in Medicine & …, 2014 - iopscience.iop.org
Recent studies have proposed that light emitted by the Cherenkov effect may be used for a
number of radiation therapy dosimetry applications. There is a correlation between the …

Imaging radiation dose in breast radiotherapy by X-ray CT calibration of Cherenkov light

RL Hachadorian, P Bruza, M Jermyn… - Nature …, 2020 - nature.com
Imaging Cherenkov emission during radiation therapy cancer treatments can provide a real-
time, non-contact sampling of the entire dose field. The emitted Cherenkov signal generated …

A review of recent and emerging approaches for the clinical application of Cerenkov luminescence imaging

B Mc Larney, M Skubal, J Grimm - Frontiers in physics, 2021 - frontiersin.org
Cerenkov luminescence is a blue-weighted emission of light produced by a vast array of
clinically approved radioisotopes and LINAC accelerators. When β particles (emitted during …

Cherenkov radiation fluence estimates in tissue for molecular imaging and therapy applications

AK Glaser, R Zhang, JM Andreozzi… - Physics in Medicine …, 2015 - iopscience.iop.org
Cherenkov radiation has recently emerged as an interesting phenomenon for a number of
applications in the biomedical sciences. Its unique properties, including broadband …

Image guidance for FLASH radiotherapy

I El Naqa, BW Pogue, R Zhang, I Oraiqat… - Medical …, 2022 - Wiley Online Library
Abstract FLASH radiotherapy (FLASH‐RT) is an emerging ultra‐high dose (> 40 Gy/s)
delivery that promises to improve the therapeutic potential by limiting toxicities compared to …

Luminescence imaging of water during irradiation of X-ray photons lower energy than Cerenkov-light threshold

S Yamamoto, S Koyama, M Komori, T Toshito - Nuclear Instruments and …, 2016 - Elsevier
Luminescence imaging of water using X-ray photon irradiation at energy lower than
maximum energy of~ 200 keV is thought to be impossible because the secondary electrons …

Real-time in vivo Cherenkoscopy imaging during external beam radiation therapy

R Zhang, DJ Gladstone, LA Jarvis… - … of biomedical optics, 2013 - spiedigitallibrary.org
Cherenkov radiation is induced when charged particles travel through dielectric media (such
as biological tissue) faster than the speed of light through that medium. Detection of this …

Cherenkov imaging method for rapid optimization of clinical treatment geometry in total skin electron beam therapy

JM Andreozzi, R Zhang, DJ Gladstone… - Medical …, 2016 - Wiley Online Library
Purpose: A method was developed utilizing Cherenkov imaging for rapid and thorough
determination of the two gantry angles that produce the most uniform treatment plane during …