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Post‐traumatic osteoarthritis of the ankle: a distinct clinical entity requiring new research approaches
The diagnosis of ankle osteoarthritis (OA) is increasing as a result of advancements in non‐
invasive imaging modalities such as magnetic resonance imaging, improved arthroscopic …
invasive imaging modalities such as magnetic resonance imaging, improved arthroscopic …
A systematic review and guide to mechanical testing for articular cartilage tissue engineering
Articular cartilage is integral to the mechanical function of many joints in the body. When
injured, cartilage lacks the capacity to self-heal, and thus, therapies and replacements have …
injured, cartilage lacks the capacity to self-heal, and thus, therapies and replacements have …
Cartilage tissue engineering in practice: preclinical trials, clinical applications, and prospects
Articular cartilage defects significantly compromise the quality of life in the global population.
Although many strategies are needed to repair articular cartilage, including microfracture …
Although many strategies are needed to repair articular cartilage, including microfracture …
Structure-function relations and rigidity percolation in the shear properties of articular cartilage
Among mammalian soft tissues, articular cartilage is particularly interesting because it can
endure a lifetime of daily mechanical loading despite having minimal regenerative capacity …
endure a lifetime of daily mechanical loading despite having minimal regenerative capacity …
Measuring microscale strain fields in articular cartilage during rapid impact reveals thresholds for chondrocyte death and a protective role for the superficial layer
Articular cartilage is a heterogeneous soft tissue that dissipates and distributes loads in
mammalian joints. Though robust, cartilage is susceptible to damage from loading at high …
mammalian joints. Though robust, cartilage is susceptible to damage from loading at high …
Effects of enzymatic treatments on the depth‐dependent viscoelastic shear properties of articular cartilage
Osteoarthritis (OA) is a disease that involves the erosion and structural weakening of
articular cartilage. OA is characterized by the degradation of collagen and proteoglycans in …
articular cartilage. OA is characterized by the degradation of collagen and proteoglycans in …
Mitoprotective therapy prevents rapid, strain‐dependent mitochondrial dysfunction after articular cartilage injury
Posttraumatic osteoarthritis (PTOA) involves the mechanical and biological deterioration of
articular cartilage that occurs following joint injury. PTOA is a growing problem in health care …
articular cartilage that occurs following joint injury. PTOA is a growing problem in health care …
Stabilized formulation for phase‐field fracture in nearly incompressible hyperelasticity
This work presents a stabilized formulation for phase‐field fracture of hyperelastic materials
near the limit of incompressibility. At this limit, traditional mixed displacement and pressure …
near the limit of incompressibility. At this limit, traditional mixed displacement and pressure …
Physiology and engineering of the graded interfaces of musculoskeletal junctions
The connective tissues of the musculoskeletal system can be grouped into fibrous,
cartilaginous, and calcified tissues. While each tissue type has a distinct composition and …
cartilaginous, and calcified tissues. While each tissue type has a distinct composition and …
Critical review on the physical and mechanical factors involved in tissue engineering of cartilage
C Gaut, K Sugaya - Regenerative medicine, 2015 - Taylor & Francis
Articular cartilage defects often progress to osteoarthritis, which negatively impacts quality of
life for millions of people worldwide and leads to high healthcare expenditures. Tissue …
life for millions of people worldwide and leads to high healthcare expenditures. Tissue …