Synthesis, characterization, and molecular modeling of phenylenediamine-phenylhydrazine-formaldehyde terpolymer (PPHF) as potent anti-inflammatory agent

N Mujafarkani, V Bassey, JJ Tokono, AJ Ahamed… - Heliyon, 2023 - cell.com
Inflammation, a characteristic physiological response to infections and tissue damage,
commences with processes involving tissue repair and pathogen elimination, contributing to …

Synthesis, biological evaluation, and molecular docking studies of novel diclofenac derivatives as antibacterial agents

MM Hamed, M Sayed, SA Abdel-Mohsen… - Journal of Molecular …, 2023 - Elsevier
In the recent years, interest in the synthesis of diclofenac derivatives has increased due to
their exceptional biological activity. We present here the synthesis of some novel diclofenac …

Diclofenac N-derivatives as therapeutic agents with anti-inflammatory and anti-cancer effect

A Galisteo, F Jannus, A García-García… - International Journal of …, 2021 - mdpi.com
A series of diclofenac N-derivatives (2, 4, 6, 8c, 9c, 10a-c) were synthesized in order to test
their anti-cancer and anti-inflammatory effects. The anticarcinogen activity has been …

Aspirin Vs Ibuprofen: Unveiling Distinct Cyclooxygenase-1/2 Behaviour and Dual Efficacy of Their Synthesized Analogues via Molecular Modeling and In-Vitro …

A Kaur, M Bansal, H Rehman, VK Mishra… - RSC Medicinal …, 2025 - pubs.rsc.org
Dual inhibition of cyclooxygenase isozymes along with platelet aggregation activities via the
arachidonic acid pathway may provide a better anti-inflammatory agent with enhanced …

Design, synthesis, antimicrobial activity, and molecular docking of some new diclofenac derivatives

MS Tolba, MM Hamed, M Sayed… - Polycyclic Aromatic …, 2023 - Taylor & Francis
Due to the biological importance of diclofenac derivatives which are included in the
composition of the active substance in many medicines used in the treatment of infections …

Novel synthetic methodology of Diclofenac derivatives and its spectrochemical studies

DR Tomar, SV Jayakumar - Materials Today: Proceedings, 2023 - Elsevier
To design the novel synthetic scheme, structural modification, characterization, and
pharmacological evaluation of new derivatives of Diclofenac drugs is the main aim of the …

Synthesis and Characterization of Novel Diclofenac (DCF) Derivatives

DR Tomar, K Mehrotra, B Bhattacharya… - Macromolecular …, 2023 - Wiley Online Library
Over the years, scientific community has shown immense interest in the synthesis of novel,
bioactive molecules with few adverse effects. Instead of painstaking multistep synthesis with …

Diclofenac N-Derivatives as Therapeutic Agents with Anti-Inflammatory and Anti-Cancer Effect

A Galisteo Pretel, F Jannus, A García García, H Aheget… - 2021 - digibug.ugr.es
A series of diclofenac N-derivatives (2, 4, 6, 8c, 9c, 10a-c) were synthesized in order to test
their anti-cancer and anti-inflammatory effects. The anticarcinogen activity has been …