Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …

The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …

Berberine, a benzylisoquinoline alkaloid, occurs as an active constituent in numerous
medicinal plants and has an array of pharmacological properties. It has been used in …

The natural product berberine (BBR) has become a potential drug in the treatment of
diabetes, hyperlipidemia, and cancer. However, the oral delivery of BBR is challenged by its …

Antibacterial drugs face increasing challenges due to drug resistance and adverse
reactions, which has created a pressing need for the discovery and development of novel …

The application of nanotechnology for antimicrobial delivery has capacity to improve
antibacterial efficacy. Currently, the usage of various inorganic and organic carriers, such as …

Virulence factor, sortase A (SrtA), has crucial roles in the pathogenesis of Gram-positive
superbugs. SrtA is a bacterial cell membrane enzyme that anchors crucial virulence factors …

Enterococcus faecalis is one of the main microorganisms that infects root canals, ranking
among the most prevalent microorganisms associated with endodontic treatment failure …

Iranian seedless barberry or zereshk (Berberis integerrima 'Bidaneh', Berberidaceae) has
long been cultivated for its fruit in South Khorasan, Iran. There are more than 11,000 ha …

Enterotoxigenic Escherichia coli (ETEC) produces two types of enterotoxins: heat-labile (LT)
and heat-stable (STa and STb). These molecules are involved in the induction of secretory …