Enzymes are a class of natural catalysts with high efficiency, specificity, and selectivity
unmatched by their synthetic counterparts and dictate a myriad of reactions that constitute …

Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Biocatalytic transformations in living organisms, such as multi-enzyme catalytic cascades,
proceed in different cellular membrane-compartmentalized organelles with high efficiency …

Biocatalytic transformations in cells, such as enzyme cascades, involve complex networks
proceeding in spatially confined microenvironments. Here, inspired by nature, we …

DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Enzyme catalysis has been attracting increasing interest in the past twenty years.
Nevertheless, most reports concerning enzyme catalysis have been carried out using single …

Patients with acute kidney injury (AKI) frequently require kidney transplantation and
supportive therapies, such as rehydration and dialysis. Here, we show that radiolabelled …

Within each biological cell, surface-and volume-confined enzymes control a highly complex
network of chemical reactions. These reactions are efficient, timely, and spatially defined …

Biocatalytic reactions in living cells involve complex transformations in the spatially confined
microenvironments. Inspired by biological transformation processes, we demonstrate …