Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

[HTML][HTML] Oxygen in stem cell biology: a critical component of the stem cell niche

A Mohyeldin, T Garzón-Muvdi, A Quiñones-Hinojosa - Cell stem cell, 2010 - cell.com
The defining hallmark of stem cells is their ability to self-renew and maintain multipotency.
This capacity depends on the balance of complex signals in their microenvironment. Low …

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …

Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair

B Marchetti, C Tirolo, F L'Episcopo, S Caniglia… - Aging cell, 2020 - Wiley Online Library
A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

Cellular mechanisms and treatments for chemobrain: insight from aging and neurodegenerative diseases

LD Nguyen, BE Ehrlich - EMBO molecular medicine, 2020 - embopress.org
Chemotherapy is a life‐saving treatment for cancer patients, but also causes long‐term
cognitive impairment, or “chemobrain”, in survivors. However, several challenges, including …

Coupling of neurogenesis and angiogenesis after ischemic stroke

L Ruan, B Wang, Q ZhuGe, K ** - Brain research, 2015 - Elsevier
Stroke is a leading cause of mortality and severe long-term disability worldwide.
Development of effective treatment or new therapeutic strategies for ischemic stroke patients …

Neurogenesis following stroke affecting the adult brain

O Lindvall, Z Kokaia - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
A bulk of experimental evidence supports the idea that the stroke-damaged adult brain
makes an attempt to repair itself by producing new neurons also in areas where …

Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors

V Kroehne, D Freudenreich, S Hans, J Kaslin… - …, 2011 - journals.biologists.com
Severe traumatic injury to the adult mammalian CNS leads to life-long loss of function. By
contrast, several non-mammalian vertebrate species, including adult zebrafish, have a …

Post‐stroke depression: mechanisms, translation and therapy

I Loubinoux, G Kronenberg, M Endres… - Journal of cellular …, 2012 - Wiley Online Library
The interaction between depression and stroke is highly complex. Post‐stroke depression
(PSD) is among the most frequent neuropsychiatric consequences of stroke. Depression …

A neurovascular niche for neurogenesis after stroke

JJ Ohab, S Fleming, A Blesch… - Journal of …, 2006 - jneurosci.org
Stroke causes cell death but also birth and migration of new neurons within sites of ischemic
damage. The cellular environment that induces neuronal regeneration and migration after …