Glutamate hypothesis in schizophrenia
Y Uno, JT Coyle - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
Schizophrenia is a chronic and severe psychiatric disorder that has profound impact on an
individual's life and on society. Thus, develo** more effective therapeutic interventions is …
individual's life and on society. Thus, develo** more effective therapeutic interventions is …
Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system
J Dalmau, C Geis, F Graus - Physiological reviews, 2017 - journals.physiology.org
Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment
Complex interactions between the immune system and the brain might have important
aetiological and therapeutic implications for neuropsychiatric brain disorders. A possible …
aetiological and therapeutic implications for neuropsychiatric brain disorders. A possible …
The origin of NMDA receptor hypofunction in schizophrenia
Abstract N-methyl-d-aspartate (NMDA) receptor (NMDAR) hypofunction plays a key role in
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …
Glutamatergic dysfunction in Schizophrenia
AO Kruse, JR Bustillo - Translational Psychiatry, 2022 - nature.com
The NMDA-R hypofunction model of schizophrenia started with the clinical observation of
the precipitation of psychotic symptoms in patients with schizophrenia exposed to PCP or …
the precipitation of psychotic symptoms in patients with schizophrenia exposed to PCP or …
Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study
N Gresa-Arribas, MJ Titulaer, A Torrents… - The Lancet …, 2014 - thelancet.com
Background Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a severe but
treatable autoimmune disorder which diagnosis depends on sensitive and specific antibody …
treatable autoimmune disorder which diagnosis depends on sensitive and specific antibody …
Schizophrenia and influenza at the centenary of the 1918-1919 Spanish influenza pandemic: mechanisms of psychosis risk
Associations between influenza infection and psychosis have been reported since the
eighteenth century, with acute “psychoses of influenza” documented during multiple …
eighteenth century, with acute “psychoses of influenza” documented during multiple …
Autoimmune encephalopathies
F Leypoldt, T Armangue… - Annals of the New York …, 2015 - Wiley Online Library
Over the past 10 years, the continual discovery of novel forms of encephalitis associated
with antibodies to cell‐surface or synaptic proteins has changed the paradigms for …
with antibodies to cell‐surface or synaptic proteins has changed the paradigms for …
Autoimmune diseases and severe infections as risk factors for schizophrenia: a 30-year population-based register study
Objective: Autoimmune diseases have been associated with an increased risk of
schizophrenia. It has been suggested that brain-reactive autoantibodies are part of the …
schizophrenia. It has been suggested that brain-reactive autoantibodies are part of the …
Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies
BackgroundDisruption of foetal development by prenatal maternal infection is consistent
with a neurodevelopmental model of schizophrenia. Whether specific prenatal infections are …
with a neurodevelopmental model of schizophrenia. Whether specific prenatal infections are …