Acinetobacter baumannii Antibiotic Resistance Mechanisms

I Kyriakidis, E Vasileiou, ZD Pana, A Tragiannidis - Pathogens, 2021 - mdpi.com
Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to
public health by causing severe and invasive (mostly nosocomial) infections linked with high …

Uncovering the mechanisms of Acinetobacter baumannii virulence

CM Harding, SW Hennon, MF Feldman - Nature Reviews Microbiology, 2018 - nature.com
Acinetobacter baumannii is a nosocomial pathogen that causes ventilator-associated as
well as bloodstream infections in critically ill patients, and the spread of multidrug-resistant …

Rescuing the last-line polymyxins: achievements and challenges

SC Nang, MAK Azad, T Velkov, QT Zhou, J Li… - Pharmacological …, 2021 - Elsevier
Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …

Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Current update on intrinsic and acquired colistin resistance mechanisms in bacteria

FA Gogry, MT Siddiqui, I Sultan, QMR Haq - Frontiers in medicine, 2021 - frontiersin.org
Colistin regained global interest as a consequence of the rising prevalence of multidrug-
resistant Gram-negative Enterobacteriaceae. In parallel, colistin-resistant bacteria emerged …

Polymyxins and bacterial membranes: a review of antibacterial activity and mechanisms of resistance

C Ayoub Moubareck - Membranes, 2020 - mdpi.com
Following their initial discovery in the 1940s, polymyxin antibiotics fell into disfavor due to
their potential clinical toxicity, especially nephrotoxicity. However, the dry antibiotic …

Resistance to polymyxins in Gram-negative organisms

K Jeannot, A Bolard, P Plesiat - International journal of antimicrobial agents, 2017 - Elsevier
Polymyxins have recently been re-introduced into the therapeutic arsenal to combat
infections caused by multidrug-resistant Gram-negative bacteria. However, the emergence …

[HTML][HTML] An overview of Acinetobacter baumannii pathogenesis: Motility, adherence and biofilm formation

HJ Mea, PVC Yong, EH Wong - Microbiological research, 2021 - Elsevier
The Gram-negative opportunistic pathogen Acinetobacter baumannii has gain notoriety in
recent decades, primarily due to its propensity to cause nosocomial infections in critically ill …

Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

Dissecting colistin resistance mechanisms in extensively drug-resistant Acinetobacter baumannii clinical isolates

V Trebosc, S Gartenmann, M Tötzl, V Lucchini… - MBio, 2019 - Am Soc Microbiol
Nosocomial infections with Acinetobacter baumannii are a global problem in intensive care
units with high mortality rates. Increasing resistance to first-and second-line antibiotics has …