Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review

MH Elkomy, AA Ali, HM Eid - Journal of Controlled Release, 2022 - Elsevier
The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

[HTML][HTML] Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

The potential of chitosan in nanomedicine: An overview of the cytotoxicity of chitosan based nanoparticles

J Frigaard, JL Jensen, HK Galtung… - Frontiers in …, 2022 - frontiersin.org
The unique properties and applications of nanotechnology in targeting drug delivery,
cosmetics, fabrics, water treatment and food packaging have received increased focus the …

Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy

M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …

[HTML][HTML] Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

Brain targeted delivery of carmustine using chitosan coated nanoparticles via nasal route for glioblastoma treatment

S Ahmad, I Khan, J Pandit, NA Emad, S Bano… - International Journal of …, 2022 - Elsevier
This study aims to develop chitosan-coated PLGA nanoparticles intended for nose-to-brain
delivery of carmustine. Formulations were prepared by the double emulsion solvent …

Nanotechnology for topical drug delivery to the anterior segment of the eye

A Vaneev, V Tikhomirova, N Chesnokova… - International journal of …, 2021 - mdpi.com
Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …

[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins

BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …

Progress and challenges of anti-VEGF agents and their sustained-release strategies for retinal angiogenesis

M Xu, R Fan, X Fan, Y Shao, X Li - Drug design, development and …, 2023 - Taylor & Francis
Currently, the treatment for ocular neovascular diseases, including diabetic macular edema
(DME) and age-related macular degeneration (AMD), mainly involves repeated intravitreal …

[HTML][HTML] Chitosan-coated PLGA nanoparticles encapsulating triamcinolone acetonide as a potential candidate for sustained ocular drug delivery

M Dandamudi, P McLoughlin, G Behl, S Rani, L Coffey… - Pharmaceutics, 2021 - mdpi.com
The current treatment for the acquired retinal vasculopathies involves lifelong repeated
intravitreal injections of either anti-vascular endothelial growth factor (VEGF) therapy or …