Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional
groups to explore and understand biology in living organisms. In this review, we summarize …

Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …

Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …

Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Chimeric antigen receptor T (CAR T) cell immunotherapy is successful at treating many
cancers. However, it often induces life-threatening cytokine release syndrome (CRS) and …

Upregulation of sialyltransferases—the enzymes responsible for the addition of sialic acid to
growing glycoconjugate chains—and the resultant hypersialylation of up to 40–60% of …

Glycans are involved in numerous biological recognition events. Being secondary gene
products, their labeling by genetic methods–comparable to GFP labeling of proteins–is not …

Disease progression is usually accompanied by changes in the biochemical composition of
cells and tissues and their biophysical properties. For instance, hallmarks of cancer include …

While the Staudinger reaction has first been described a hundred years ago in 1919, the
ligation reaction became one of the most important and efficient bioconjugation techniques …