Sumoylation is an essential post-translational modification that is catalysed by a small
number of modifying enzymes but regulates thousands of target proteins in a dynamic …

Posttranslational modifications (PTMs) refer to amino acid side chain modification in some
proteins after their biosynthesis. There are more than 400 different types of PTMs affecting …

Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates
multiple biological processes, including cell division, DNA replication/repair, signal …

The nuclear pore complex (NPC) serves as the sole bidirectional gateway of
macromolecules in and out of the nucleus. Owing to its size and complexity (∼ 1,000 protein …

Post-translational protein modification by small ubiquitin-like modifier (SUMO), termed
sumoylation, is an important mechanism in cellular responses to stress and one that …

SUMOylation is a reversible post-translational modification which has emerged as a crucial
molecular regulatory mechanism, involved in the regulation of DNA damage repair, immune …

Small ubiquitin-like modifiers (SUMOs) are post-translational modifications (PTMs) that
regulate nuclear cellular processes. Here we used an augmented K0–SUMO proteomics …

Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …

RING finger domain and RING finger-like ubiquitin ligases (E3s), such as U-box proteins,
constitute the vast majority of known E3s. RING-type E3s function together with ubiquitin …

SUMOylation is a reversible post-translational modification essential for genome stability.
Using high-resolution MS, we have studied global SUMOylation in human cells in a site …