Since the inception of lung transplantation (LTx), serial pulmonary function testing (PFT) has
been the primary method of quantifying the physiologic performance of the allograft. The …

A growing number of patients with end-stage lung disease have benefited from lung
transplantation (LT). Improvements in organ procurement, surgical techniques and intensive …

Lung transplantation (LTx) has evolved significantly since its inception and the improvement
in LTx outcomes over the last three decades has predominantly been driven by advances in …

We previously established a six-gene–based blood score associated with operational
tolerance in kidney transplantation which was decreased in patients develo** anti-HLA …

Bronchiolitis obliterans syndrome (BOS) is the most common form of CLAD and is
characterized by airflow limitation and an obstructive spirometric pattern without high …

Despite much progress in the management of kidney transplantation, the need for life-long
immunosuppressive therapies remains a major issue representing many risks for patients …

In both research and care, patients, caregivers, and researchers are facing a leap forward in
the quantity of data that are available for analysis and interpretation, marking the daunting …

Background Many lung transplants fail due to chronic lung allograft dysfunction (CLAD). We
recently showed that transbronchial biopsies (TBBs) from CLAD patients manifest severe …

Background Connective tissue growth factor (CTGF) is an important mediator in several
fibrotic diseases, including lung fibrosis. We investigated CTGF-expression in chronic lung …

Until now, the ability to predict or retard immune-mediated rejection events after lung
transplantation is still limited due to the lack of specific biomarkers. The pressing need …