The impact of dietary fiber on gut microbiota in host health and disease

K Makki, EC Deehan, J Walter, F Bäckhed - Cell host & microbe, 2018 - cell.com
Food is a primordial need for our survival and well-being. However, diet is not only essential
to maintain human growth, reproduction, and health, but it also modulates and supports the …

The obese adipose tissue microenvironment in cancer development and progression

DF Quail, AJ Dannenberg - Nature Reviews Endocrinology, 2019 - nature.com
Obesity is associated with both increased cancer incidence and progression in multiple
tumour types, and is estimated to contribute to up to 20% of cancer-related deaths. These …

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

B Vandanmagsar, YH Youm, A Ravussin, JE Galgani… - Nature medicine, 2011 - nature.com
The emergence of chronic inflammation during obesity in the absence of overt infection or
well-defined autoimmune processes is a puzzling phenomenon. The Nod-like receptor …

Impact of obesity on influenza A virus pathogenesis, immune response, and evolution

R Honce, S Schultz-Cherry - Frontiers in immunology, 2019 - frontiersin.org
With the rising prevalence of obesity has come an increasing awareness of its impact on
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …

[HTML][HTML] Impact of obesity and metabolic syndrome on immunity

CJ Andersen, KE Murphy, ML Fernandez - Advances in Nutrition, 2016 - Elsevier
Obesity is associated with metabolic disturbances that cause tissue stress and dysfunction.
Obese individuals are at a greater risk for chronic disease and often present with clinical …

Obesity is associated with increased severity of disease in COVID-19 pneumonia: a systematic review and meta-analysis

Y Chu, J Yang, J Shi, P Zhang, X Wang - European journal of medical …, 2020 - Springer
Background Obesity has been widely reported to be associated with the disease
progression of coronavirus disease 2019 (COVID-19); however, some studies have reported …

The obesity-breast cancer link: a multidisciplinary perspective

EN Devericks, MS Carson, LE McCullough… - Cancer and Metastasis …, 2022 - Springer
Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Nutrition, inflammation and cancer

L Zitvogel, F Pietrocola, G Kroemer - Nature immunology, 2017 - nature.com
Quantitative and qualitative aspects of nutrition have a profound effect on leukocytes and
thereby affect proinflammatory carcinogenic effects or anticancer immune responses. As a …

Age-associated remodeling of T cell immunity and metabolism

SJ Han, P Georgiev, AE Ringel, AH Sharpe, MC Haigis - Cell metabolism, 2023 - cell.com
Aging results in remodeling of T cell immunity and is associated with poor clinical outcomes
in age-related diseases such as cancer. Among the hallmarks of aging, changes in host and …

Obesity is associated with impaired immune response to influenza vaccination in humans

PA Sheridan, HA Paich, J Handy, EA Karlsson… - International journal of …, 2012 - nature.com
Background: Obesity is an independent risk factor for morbidity and mortality from pandemic
influenza H1N1. Influenza is a significant public health threat, killing an estimated 250 000 …