A serum-free culture medium production system by co-culture combining growth factor-secreting cells and l-lactate-assimilating cyanobacteria for sustainable cultured …

S Chu, Y Haraguchi, T Asahi, Y Kato, A Kondo… - Scientific Reports, 2024 - nature.com
Large-scale production of cultured meat requires bulk culture medium containing growth-
promoting proteins from animal serum. However, animal serum for mammalian cell culture is …

Cyanobacterial green chemistry: a blue-green approach for a sustainable environment, energy, and chemical production

P Pandey, D Pandey, A Gupta, R Gupta, S Tiwari… - RSC …, 2025 - pubs.rsc.org
Increased human activity due to the ever-increasing global population has necessitated the
urgent need for a sustainable environment, food, and energy. Cyanobacteria, classically …

Glycogen deficiency enhances carbon partitioning into glutamate for an alternative extracellular metabolic sink in cyanobacteria

Y Kato, R Hidese, M Matsuda, R Ohbayashi… - Communications …, 2024 - nature.com
Glycogen serves as a metabolic sink in cyanobacteria. Glycogen deficiency causes the
extracellular release of distinctive metabolites such as pyruvate and 2-oxoglutarate upon …

Pioneering precision in markerless strain development for Synechococcus sp. PCC 7002

A Tsuji, K Inabe, R Hidese, Y Kato, L Domingues… - Microbial Cell …, 2024 - Springer
Marine cyanobacteria such as Picosynechococcus sp.(formerly called Synechococcus sp.)
PCC 7002 are promising chassis for photosynthetic production of commodity chemicals with …

Metabolic analysis reveals the contribution of mechanosensitive channel MscM to extracellular release of glutamate in glycogen-deficient Synechococcus elongatus

Y Kato, K Kamasaka, M Matsuda, H Koizumi… - Journal of Bioscience …, 2024 - Elsevier
In bacteria, mechanosensitive channels mediate extracellular release of osmolytes,
including glutamate, functioning as safety valves upon osmotic downshift. In cyanobacteria …

Circular cell culture for sustainable food production using recombinant lactate-assimilating cyanobacteria that supplies pyruvate and amino acids

Y Haraguchi, Y Kato, K Inabe, A Kondo… - Archives of …, 2023 - Springer
Recently, we reported a circular cell culture (CCC) system using microalgae and animal
muscle cells for sustainable culture food production. However, lactate accumulation …

Impact of Zero-Valent Iron Nanoparticles and Ampicillin on Adenosine Triphosphate and Lactate Metabolism in the Cyanobacterium Fremyella diplosiphon

YS Yalcin, BN Aydin, V Sitther - Microorganisms, 2024 - mdpi.com
In cyanobacteria, the interplay of ATP and lactate dynamics underpins cellular energetics;
their pronounced shifts in response to zero-valent iron (nZVI) nanoparticles and ampicillin …

Recombinant lactate-assimilating cyanobacteria reduce high-concentration culture-associated cytotoxicity in mammalian cells

Y Haraguchi, Y Kato, A Tsuji, T Hasunuma… - Archives of …, 2024 - Springer
In the fields of cultured meat, biopharmaceuticals, cell therapy, and tissue engineering, large
numbers of mammalian cells are required; thus, highly-concentrated cell cultures are widely …

植物乳杆菌素的抑菌特性及应用研究进展.

满丽莉, 向殿军 - China Condiment, 2024 - search.ebscohost.com
植物乳杆菌素是由多个氨基酸组成的抑菌物质, 因其稳定性高, 安全性高, 来源广泛,
抑菌效果好等优势成为研究和关注的热点. 植物乳杆菌素在食品, 畜禽生产 …

MAKING LAB-GROWN MEAT MORE SUSTAINABLE

W NOT, W NOT - nature.com
In the future,'circular cell culture systems'(pictured in this illustration) could use algae-based
innovations to minimize the environmental impact of lab-grown meat. Credit: Yuki …