Researchers have discovered associations between elements of the intestinal microbiome
(including specific microbes, signaling pathways, and microbiota-related metabolites) and …

The substantial burden of colorectal cancer and increasing trend in young adults highlight
the importance of lifestyle modification as a complement to screening for colorectal cancer …

Background and Aims Cancer‐associated fibroblasts (CAFs) are key players in multicellular,
stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …

Because of the absence of effective gallstone formation prevention, targets against the
metabolic changes in obesity should be further explored in randomized controlled trials. To …

The high prevalence of cholesterol gallstones, the availability of new information about
pathogenesis, and the relevant health costs due to the management of cholelithiasis in both …

Cholesterol gallstone (CGS) disease is characterized by an imbalance in bile acid (BA)
metabolism and is closely associated with gut microbiota disorders. However, the role and …

The world is witnessing a global increase in the urban population, particularly in develo**
Asian and African countries. Concomitantly, the global burden of non-communicable …

Background and Aims Gallbladder cancer (GBC) is a neglected disease with substantial
geographical variability: Chile shows the highest incidence worldwide, while GBC is …

Evidence links the liver to development of colorectal cancer (CRC). However, it remains
unknown how liver function may influence CRC risk in the general population. We …

Gut microbiota is a complex ecosystem of symbiotic bacteria that contribute to human
metabolism and supply intestinal metabolites, whose production is mainly influenced by the …