Self-assembly of surfactants: An overview on general aspects of amphiphiles
Surfactants are molecules (ionic or nonionic) that upon adsorption at the air-water interface
reduce surface tension of water. Therefore, surfactants are surface-active agents …
reduce surface tension of water. Therefore, surfactants are surface-active agents …
Amphipols from A to Z
JL Popot, T Althoff, D Bagnard… - Annual review of …, 2011 - annualreviews.org
Amphipols (APols) are short amphipathic polymers that can substitute for detergents to keep
integral membrane proteins (MPs) water soluble. In this review, we discuss their structure …
integral membrane proteins (MPs) water soluble. In this review, we discuss their structure …
[HTML][HTML] Crystallogenesis of membrane proteins mediated by polymer-bounded lipid nanodiscs
J Broecker, BT Eger, OP Ernst - Structure, 2017 - cell.com
For some membrane proteins, detergent-mediated solubilization compromises protein
stability and functionality, often impairing biophysical and structural analyses. Hence …
stability and functionality, often impairing biophysical and structural analyses. Hence …
Bacterial reaction centers purified with styrene maleic acid copolymer retain native membrane functional properties and display enhanced stability
DJK Swainsbury, S Scheidelaar… - Angewandte …, 2014 - Wiley Online Library
Integral membrane proteins often present daunting challenges for biophysical
characterization, a fundamental issue being how to select a surfactant that will optimally …
characterization, a fundamental issue being how to select a surfactant that will optimally …
[HTML][HTML] Characterization of the annular lipid shell of the Sec translocon
The bacterial Sec translocase in its minimal form consists of a membrane-embedded protein-
conducting pore SecYEG that interacts with the motor protein SecA to mediate the …
conducting pore SecYEG that interacts with the motor protein SecA to mediate the …
Amphipols for each season
M Zoonens, JL Popot - The Journal of membrane biology, 2014 - Springer
Amphipols (APols) are short amphipathic polymers that can substitute for detergents at the
transmembrane surface of membrane proteins (MPs) and, thereby, keep them soluble in …
transmembrane surface of membrane proteins (MPs) and, thereby, keep them soluble in …
Advances in the mass spectrometry of membrane proteins: from individual proteins to intact complexes
Rapid advances in structural genomics and in large-scale proteomic projects have yielded
vast amounts of data on soluble proteins and their complexes. Despite these advances …
vast amounts of data on soluble proteins and their complexes. Despite these advances …
Large-scale production and protein engineering of G protein-coupled receptors for structural studies
Structural studies of G protein-coupled receptors (GPCRs) gave insights into molecular
mechanisms of their action and contributed significantly to molecular pharmacology. This is …
mechanisms of their action and contributed significantly to molecular pharmacology. This is …
Oligomeric assembly of the C-terminal and transmembrane region of SARS-CoV-2 nsp3
M Babot, Y Boulard, S Agouda, L Pieri… - Journal of …, 2024 - Am Soc Microbiol
As for all single-stranded, positive-sense RNA (+ RNA) viruses, intracellular RNA synthesis
relies on extensive remodeling of host cell membranes that leads to the formation of …
relies on extensive remodeling of host cell membranes that leads to the formation of …
Nonionic homopolymeric amphipols: application to membrane protein folding, cell-free synthesis, and solution nuclear magnetic resonance
Nonionic amphipols (NAPols) synthesized by homotelomerization of an amphiphatic
monomer are able to keep membrane proteins (MPs) stable and functional in the absence of …
monomer are able to keep membrane proteins (MPs) stable and functional in the absence of …