Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective

S Kumariya, V Ubba, RK Jha, JR Gayen - Autophagy, 2021 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a unification of endocrine and metabolic disorders and
has become immensely prevalent among women of fertile age. The prime organ affected in …

Making a good egg: human oocyte health, aging, and in vitro development

EE Telfer, J Grosbois, YL Odey… - Physiological …, 2023 - journals.physiology.org
Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited

RL Rosenfield, DA Ehrmann - Endocrine reviews, 2016 - academic.oup.com
Polycystic ovary syndrome (PCOS) was hypothesized to result from functional ovarian
hyperandrogenism (FOH) due to dysregulation of androgen secretion in 1989–1995 …

Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells

M Wagner, M Yoshihara, I Douagi… - Nature …, 2020 - nature.com
The human ovary orchestrates sex hormone production and undergoes monthly structural
changes to release mature oocytes. The outer lining of the ovary (cortex) has a key role in …

Clinical management of congenital hypogonadotropic hypogonadism

J Young, C Xu, GE Papadakis, JS Acierno… - Endocrine …, 2019 - academic.oup.com
The initiation and maintenance of reproductive capacity in humans is dependent on pulsatile
secretion of the hypothalamic hormone GnRH. Congenital hypogonadotropic hypogonadism …

Interactions between androgens, FSH, anti-Müllerian hormone and estradiol during folliculogenesis in the human normal and polycystic ovary

D Dewailly, G Robin, M Peigne… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Androgens, FSH, anti-Müllerian hormone (AMH) and estradiol (E2) are
essential in human ovarian folliculogenesis. However, the interactions between these four …

Intraovarian control of early folliculogenesis

AJW Hsueh, K Kawamura, Y Cheng… - Endocrine …, 2015 - academic.oup.com
Although hormonal regulation of ovarian follicle development has been extensively
investigated, most studies concentrate on the development of early antral follicles to the …

[HTML][HTML] Oocyte environment: follicular fluid and cumulus cells are critical for oocyte health

DA Dumesic, DR Meldrum, MG Katz-Jaffe, RL Krisher… - Fertility and sterility, 2015 - Elsevier
Bidirectional somatic cell–oocyte signaling is essential to create a changing intrafollicular
microenvironment that controls primordial follicle growth into a cohort of growing follicles …

The signaling pathways involved in ovarian follicle development

L Li, X Shi, Y Shi, Z Wang - Frontiers in Physiology, 2021 - frontiersin.org
The follicle is the functional unit of the ovary, which is composed of three types of cells:
oocytes, granulosa cells, and theca cells. Ovarian follicle development and the subsequent …

ESHRE consensus on the definition of 'poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria

AP Ferraretti, A La Marca, B Fauser… - Human …, 2011 - academic.oup.com
The definition presented here represents the first realistic attempt by the scientific community
to standardize the definition of poor ovarian response (POR) in a simple and reproducible …