Hyperuricemia and its related diseases: mechanisms and advances in therapy
L Du, Y Zong, H Li, Q Wang, L **e, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …
Uric acid and hypertension: a review of evidence and future perspectives for the management of cardiovascular risk
Uric acid is the final product of purine metabolism, and its increased serum levels have been
directly involved in the pathogenesis and natural history of hypertension. The relationship …
directly involved in the pathogenesis and natural history of hypertension. The relationship …
2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of …
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
Biobanks facilitate genome-wide association studies (GWASs), which have mapped
genomic loci across a range of human diseases and traits. However, most biobanks are …
genomic loci across a range of human diseases and traits. However, most biobanks are …
Association of serum uric acid with all-cause and cardiovascular mortality in diabetes
B Li, L Chen, X Hu, T Tan, J Yang, W Bao… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE To investigate whether serum uric acid (SUA) level is associated with all-cause
and cardiovascular disease (CVD) mortality among individuals with diabetes. RESEARCH …
and cardiovascular disease (CVD) mortality among individuals with diabetes. RESEARCH …
Mendelian randomization as a tool for cardiovascular research: a review
Importance Mendelian randomization (MR) is a statistical approach that has become
increasingly popular in the field of cardiovascular disease research. It offers a way to infer …
increasingly popular in the field of cardiovascular disease research. It offers a way to infer …
Excess comorbidities in gout: the causal paradigm and pleiotropic approaches to care
Gout is a common hyperuricaemic metabolic condition that leads to painful inflammatory
arthritis and a high comorbidity burden, especially cardiometabolic-renal (CMR) conditions …
arthritis and a high comorbidity burden, especially cardiometabolic-renal (CMR) conditions …
[HTML][HTML] Flexible electronics for cardiovascular healthcare monitoring
Cardiovascular diseases (CVDs) are one of the most urgent threats to humans worldwide,
which are responsible for almost one-third of global mortality. Over the last decade, research …
which are responsible for almost one-third of global mortality. Over the last decade, research …
Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study
The risk factors for nonalcoholic fatty liver disease (NAFLD) have not been clearly identified.
We conducted a Mendelian randomization (MR) study to explore this. Independent genetic …
We conducted a Mendelian randomization (MR) study to explore this. Independent genetic …
[HTML][HTML] Uric acid and chronic kidney disease: still more to do
Gout and hyperuricemia are present in 25% and 60% of patients with chronic kidney
disease (CKD), respectively. Despite the common association, the role of uric acid in the …
disease (CKD), respectively. Despite the common association, the role of uric acid in the …