Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

Importance Mendelian randomization (MR) is a statistical approach that has become
increasingly popular in the field of cardiovascular disease research. It offers a way to infer …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Biobanks facilitate genome-wide association studies (GWASs), which have mapped
genomic loci across a range of human diseases and traits. However, most biobanks are …

OBJECTIVE To investigate whether serum uric acid (SUA) level is associated with all-cause
and cardiovascular disease (CVD) mortality among individuals with diabetes. RESEARCH …

Cardiovascular diseases (CVDs) are one of the most urgent threats to humans worldwide,
which are responsible for almost one-third of global mortality. Over the last decade, research …

Uric acid is the final product of purine metabolism, and its increased serum levels have been
directly involved in the pathogenesis and natural history of hypertension. The relationship …

Gout and hyperuricemia are present in 25% and 60% of patients with chronic kidney
disease (CKD), respectively. Despite the common association, the role of uric acid in the …

The prevalence of patients with hyperuricemia or gout is increasing worldwide.
Hyperuricemia and gout are primarily attributed to genetic factors, along with lifestyle factors …

A direct relationship between serum uric acid levels and hypertension, cardiovascular, renal
and metabolic diseases has been reported in many basic and epidemiological studies …